Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux

Abstract Cells often alter metabolic strategies under nutrient-deprived conditions to support their survival and growth. Characterizing metabolic reprogramming in the tumor microenvironment (TME) is of emerging importance in cancer research and patient care. However, recent technologies only measure...

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Hlavní autoři: Yuefan Huang, Vakul Mohanty, Merve Dede, Kyle Tsai, May Daher, Li Li, Katayoun Rezvani, Ken Chen
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2023-08-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-023-40457-w