Recent Progress in the Understanding and Engineering of Coenzyme B12-Dependent Glycerol Dehydratase

Recent Progress in the Understanding and Engineering of Coenzyme B12-Dependent Glycerol Dehydratase

Coenzyme B12-dependent glycerol dehydratase (GDHt) catalyzes the dehydration reaction of glycerol in the presence of adenosylcobalamin to yield 3-hydroxypropanal (3-HPA), which can be converted biologically to versatile platform chemicals such as 1,3-propanediol and 3-hydroxypropionic acid. Owing to...

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Bibliographic Details
Main Authors:	Abdul Nasir, Somasundar Ashok, Jeung Yeop Shim, Sunghoon Park, Tae Hyeon Yoo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	glycerol dehydratase coenzyme B12 glycerol inactivation reactivase enzyme engineering
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2020.500867/full

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