Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke
Objective: To determine the frequency, risk factors, and impact on the outcome of dehydration after stroke.Methods: In this cross-sectional observational study, we included prospectively and consecutively patients with ischemic and hemorrhagic stroke. The serum Urea/Creatinine ratio (U/C) was calcul...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-03-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.00305/full |
| _version_ | 1811222869099675648 |
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| author | Elena Cortés-Vicente Daniel Guisado-Alonso Raquel Delgado-Mederos Pol Camps-Renom Luis Prats-Sánchez Alejandro Martínez-Domeño Joan Martí-Fàbregas |
| author_facet | Elena Cortés-Vicente Daniel Guisado-Alonso Raquel Delgado-Mederos Pol Camps-Renom Luis Prats-Sánchez Alejandro Martínez-Domeño Joan Martí-Fàbregas |
| author_sort | Elena Cortés-Vicente |
| collection | DOAJ |
| description | Objective: To determine the frequency, risk factors, and impact on the outcome of dehydration after stroke.Methods: In this cross-sectional observational study, we included prospectively and consecutively patients with ischemic and hemorrhagic stroke. The serum Urea/Creatinine ratio (U/C) was calculated at admission and 3 days after the stroke. Dehydration was defined as U/C>80. Patients were treated in accordance with the standard local hydration protocol. Demographic and clinical data were collected. Neurological severity was evaluated at admission according to the NIHSS score; functional outcome was assessed with the modified Rankin scale score (mRS) at discharge and 3 months after the stroke. Unfavorable outcome was defined as mRS > 2.Results: We evaluated 203 patients; 78.8% presented an ischemic stroke and 21.2% a hemorrhagic stroke. The mean age was 73.4 years ±12.9; 51.7% were men. Dehydration was detected in 18 patients (8.9%), nine patients at admission (4.5%), and nine patients (4.5%) at 3 days after the stroke. Female sex (OR 3.62, 95%CI 1.13–11.58, p = 0.03) and older age (OR 1.05, 95%CI 1–1.11, p = 0.048) were associated with a higher risk of dehydration. Dehydration was significantly associated with an unfavorable outcome at discharge (OR 5.16, 95%CI 1.45–18.25, p = 0.011), but the association was not significant at 3 months (OR 2.95, 95%CI 0.83–10.48, p = 0.095).Conclusion: Dehydration is a treatable risk factor of a poor functional outcome after stroke that is present in 9% of patients. Females and elders present a higher risk of dehydration. |
| first_indexed | 2024-04-12T08:22:08Z |
| format | Article |
| id | doaj.art-6eb090fb63914e7fbb7a05174d296928 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-12T08:22:08Z |
| publishDate | 2019-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-6eb090fb63914e7fbb7a05174d2969282022-12-22T03:40:32ZengFrontiers Media S.A.Frontiers in Neurology1664-22952019-03-011010.3389/fneur.2019.00305452789Frequency, Risk Factors, and Prognosis of Dehydration in Acute StrokeElena Cortés-VicenteDaniel Guisado-AlonsoRaquel Delgado-MederosPol Camps-RenomLuis Prats-SánchezAlejandro Martínez-DomeñoJoan Martí-FàbregasObjective: To determine the frequency, risk factors, and impact on the outcome of dehydration after stroke.Methods: In this cross-sectional observational study, we included prospectively and consecutively patients with ischemic and hemorrhagic stroke. The serum Urea/Creatinine ratio (U/C) was calculated at admission and 3 days after the stroke. Dehydration was defined as U/C>80. Patients were treated in accordance with the standard local hydration protocol. Demographic and clinical data were collected. Neurological severity was evaluated at admission according to the NIHSS score; functional outcome was assessed with the modified Rankin scale score (mRS) at discharge and 3 months after the stroke. Unfavorable outcome was defined as mRS > 2.Results: We evaluated 203 patients; 78.8% presented an ischemic stroke and 21.2% a hemorrhagic stroke. The mean age was 73.4 years ±12.9; 51.7% were men. Dehydration was detected in 18 patients (8.9%), nine patients at admission (4.5%), and nine patients (4.5%) at 3 days after the stroke. Female sex (OR 3.62, 95%CI 1.13–11.58, p = 0.03) and older age (OR 1.05, 95%CI 1–1.11, p = 0.048) were associated with a higher risk of dehydration. Dehydration was significantly associated with an unfavorable outcome at discharge (OR 5.16, 95%CI 1.45–18.25, p = 0.011), but the association was not significant at 3 months (OR 2.95, 95%CI 0.83–10.48, p = 0.095).Conclusion: Dehydration is a treatable risk factor of a poor functional outcome after stroke that is present in 9% of patients. Females and elders present a higher risk of dehydration.https://www.frontiersin.org/article/10.3389/fneur.2019.00305/fullstrokedehydrationureacreatinineprognosisrisk factors |
| spellingShingle | Elena Cortés-Vicente Daniel Guisado-Alonso Raquel Delgado-Mederos Pol Camps-Renom Luis Prats-Sánchez Alejandro Martínez-Domeño Joan Martí-Fàbregas Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke Frontiers in Neurology stroke dehydration urea creatinine prognosis risk factors |
| title | Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| title_full | Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| title_fullStr | Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| title_full_unstemmed | Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| title_short | Frequency, Risk Factors, and Prognosis of Dehydration in Acute Stroke |
| title_sort | frequency risk factors and prognosis of dehydration in acute stroke |
| topic | stroke dehydration urea creatinine prognosis risk factors |
| url | https://www.frontiersin.org/article/10.3389/fneur.2019.00305/full |
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