Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial
Fermented food has been demonstrated to increase immunity, protect against pathogens, and improve cancer survival. However, the relationship between fermented vegetables and immunotherapy has not been tested. We conducted a randomized controlled trial. The experimental group (n = 36) was supplemente...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464622004200 |
| _version_ | 1811201683073531904 |
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| author | Nan Lin Tingting Dai Jing Zhou Hexiao Huang Hong Yun Zhenyu Ding Xuelei Ma |
| author_facet | Nan Lin Tingting Dai Jing Zhou Hexiao Huang Hong Yun Zhenyu Ding Xuelei Ma |
| author_sort | Nan Lin |
| collection | DOAJ |
| description | Fermented food has been demonstrated to increase immunity, protect against pathogens, and improve cancer survival. However, the relationship between fermented vegetables and immunotherapy has not been tested. We conducted a randomized controlled trial. The experimental group (n = 36) was supplemented with fermented vegetable enzyme every day for 2 cycles of immunotherapy, while the control group (n = 36) received a normal diet. The treatment response, nutritional and immunological indexes were collected at baseline and after 2 cycles of therapy. After comparing the baseline and the follow-up CT, no significant difference was found between the two groups. The hemoglobin, FT4, AST, albumin, LDL-C, and IgG indexes were better in the experimental group, meaning the side effects of immunotherapy in esophageal cancer patients. Fermented foods can alleviate the side effects of esophageal cancer immunotherapy combined with chemotherapy to a certain extent, such as anemia, malnutrition, and elevated AST. |
| first_indexed | 2024-04-12T02:25:37Z |
| format | Article |
| id | doaj.art-6eb112af5d1f471f9b1523d9c897155a |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-12T02:25:37Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-6eb112af5d1f471f9b1523d9c897155a2022-12-22T03:52:00ZengElsevierJournal of Functional Foods1756-46462022-12-0199105350Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trialNan Lin0Tingting Dai1Jing Zhou2Hexiao Huang3Hong Yun4Zhenyu Ding5Xuelei Ma6Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Clinical Nutrition, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, China; Corresponding author at: West China Hospital, Guoxue Lane 37, Chengdu, China.Fermented food has been demonstrated to increase immunity, protect against pathogens, and improve cancer survival. However, the relationship between fermented vegetables and immunotherapy has not been tested. We conducted a randomized controlled trial. The experimental group (n = 36) was supplemented with fermented vegetable enzyme every day for 2 cycles of immunotherapy, while the control group (n = 36) received a normal diet. The treatment response, nutritional and immunological indexes were collected at baseline and after 2 cycles of therapy. After comparing the baseline and the follow-up CT, no significant difference was found between the two groups. The hemoglobin, FT4, AST, albumin, LDL-C, and IgG indexes were better in the experimental group, meaning the side effects of immunotherapy in esophageal cancer patients. Fermented foods can alleviate the side effects of esophageal cancer immunotherapy combined with chemotherapy to a certain extent, such as anemia, malnutrition, and elevated AST.http://www.sciencedirect.com/science/article/pii/S1756464622004200ImmunotherapyFermented vegetableEsophageal cancer |
| spellingShingle | Nan Lin Tingting Dai Jing Zhou Hexiao Huang Hong Yun Zhenyu Ding Xuelei Ma Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial Journal of Functional Foods Immunotherapy Fermented vegetable Esophageal cancer |
| title | Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial |
| title_full | Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial |
| title_fullStr | Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial |
| title_full_unstemmed | Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial |
| title_short | Evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy: A randomized controlled trial |
| title_sort | evaluation of the nutritional index and immunological function of a fermented vegetable for esophageal cancer patients undergoing immunotherapy plus chemotherapy a randomized controlled trial |
| topic | Immunotherapy Fermented vegetable Esophageal cancer |
| url | http://www.sciencedirect.com/science/article/pii/S1756464622004200 |
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