Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?

Abstract Asymptomatic bacteriuria (ABU) is one of the most common problems during pregnancy. In our public health system, screening of ABU by urinalysis (UA) is free for all pregnant women but urine culture (UC) is more sensitive and specific than UA. Determination of condition to screeni...

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Main Authors: Ziba Farajzadegan, Parisa Mirmoghtadaee, Ferdos Mehrabian
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2008-09-01
Series:مجله دانشکده پزشکی اصفهان
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/122
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author Ziba Farajzadegan
Parisa Mirmoghtadaee
Ferdos Mehrabian
author_facet Ziba Farajzadegan
Parisa Mirmoghtadaee
Ferdos Mehrabian
author_sort Ziba Farajzadegan
collection DOAJ
description Abstract Asymptomatic bacteriuria (ABU) is one of the most common problems during pregnancy. In our public health system, screening of ABU by urinalysis (UA) is free for all pregnant women but urine culture (UC) is more sensitive and specific than UA. Determination of condition to screening asymptomatic bacteriuria with urine culture was the main field of the study. Background: 200 pregnant women in two groups were screened by Dipstick UA and UC. Costs (6) were calculated per groups, and prevented symptomatic bacteriuria was considered as effectiveness (E). Proportion of C/E was estimated. Sensitivity analysis was performed over wide ranges of prevalence of asymptomatic bacteriuria (ASB). Methods: Prevalence of bacteriuria was 4 percent. Direct costs in leukocyte esterase- nitrite dipstick group were 723600 Rials and in leukocyte esterase- nitrite dipstick + urine culture group were 1788800 Rials. The incremental costs in first group were 70200 Rials and cost savings in second group were 46800 Rials. The prevention ratio in first group was 55 percent, and in urinalysis +urine culture was 100 percent. The cost- effectiveness ratio in first group was 1.3 and in second group was 1.7. In sensitivity analysis, if prevalence of ASB was 13 percent، -effectiveness of these strategies were equal and if prevalence was 14 percent and higher, the cost- effectiveness with leukocyte esterase- nitrite dipstick+ urine culture was lower than leukocyte esterase- nitrite dipstick group. Findings: According to our findings, prevalence of ABU was low, screening of ABU by UA in public system is cost/effective at the present situation, but epidemiologic trend study is necessary to make decision about screening tools. Conclusion: Isfahan, ABU, screening, cost-effectiveness, urine culture, urine analysis, pregnancy. Key words:
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spelling doaj.art-6eb2e95ff8144d11ab865948c01e13a02023-09-02T16:09:12ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2008-09-012689119Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?Ziba Farajzadegan0Parisa Mirmoghtadaee1Ferdos Mehrabian2Associate Professor of Community Medicine, School of Medicine, Isfahan University of Medical Science, Isfahsn, IranCommunity Medicine, School of pharmacy, Isfahan University of Medical Science, Isfahan, Iran.Associate Professor of Gynecology, School of Medicine, Isfahan University of Medical Science, Isfahan, IranAbstract Asymptomatic bacteriuria (ABU) is one of the most common problems during pregnancy. In our public health system, screening of ABU by urinalysis (UA) is free for all pregnant women but urine culture (UC) is more sensitive and specific than UA. Determination of condition to screening asymptomatic bacteriuria with urine culture was the main field of the study. Background: 200 pregnant women in two groups were screened by Dipstick UA and UC. Costs (6) were calculated per groups, and prevented symptomatic bacteriuria was considered as effectiveness (E). Proportion of C/E was estimated. Sensitivity analysis was performed over wide ranges of prevalence of asymptomatic bacteriuria (ASB). Methods: Prevalence of bacteriuria was 4 percent. Direct costs in leukocyte esterase- nitrite dipstick group were 723600 Rials and in leukocyte esterase- nitrite dipstick + urine culture group were 1788800 Rials. The incremental costs in first group were 70200 Rials and cost savings in second group were 46800 Rials. The prevention ratio in first group was 55 percent, and in urinalysis +urine culture was 100 percent. The cost- effectiveness ratio in first group was 1.3 and in second group was 1.7. In sensitivity analysis, if prevalence of ASB was 13 percent، -effectiveness of these strategies were equal and if prevalence was 14 percent and higher, the cost- effectiveness with leukocyte esterase- nitrite dipstick+ urine culture was lower than leukocyte esterase- nitrite dipstick group. Findings: According to our findings, prevalence of ABU was low, screening of ABU by UA in public system is cost/effective at the present situation, but epidemiologic trend study is necessary to make decision about screening tools. Conclusion: Isfahan, ABU, screening, cost-effectiveness, urine culture, urine analysis, pregnancy. Key words:http://jims.mui.ac.ir/index.php/jims/article/view/122
spellingShingle Ziba Farajzadegan
Parisa Mirmoghtadaee
Ferdos Mehrabian
Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
مجله دانشکده پزشکی اصفهان
title Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
title_full Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
title_fullStr Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
title_full_unstemmed Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
title_short Screening of asymptomatic bacteriuria: Urinalysis or Urine culture? Which one is more cost- effective?
title_sort screening of asymptomatic bacteriuria urinalysis or urine culture which one is more cost effective
url http://jims.mui.ac.ir/index.php/jims/article/view/122
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AT parisamirmoghtadaee screeningofasymptomaticbacteriuriaurinalysisorurineculturewhichoneismorecosteffective
AT ferdosmehrabian screeningofasymptomaticbacteriuriaurinalysisorurineculturewhichoneismorecosteffective