Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa
Rabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco. In addition to the classical virus (RHDV), a novel emerged genotype (RHDV2) is circulating, es...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2022-12-01
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| Series: | Acta Veterinaria |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acve-2022-0035 |
| _version_ | 1797947606575349760 |
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| author | Saidi Aissa Aboutaib Abdelouahed |
| author_facet | Saidi Aissa Aboutaib Abdelouahed |
| author_sort | Saidi Aissa |
| collection | DOAJ |
| description | Rabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco. In addition to the classical virus (RHDV), a novel emerged genotype (RHDV2) is circulating, especially in the north shore of the Mediterranean basin since 2010. Many small animal farmers reported clinical cases from several rabbitries in Agadir (Morocco) despite systematic vaccination against the RHDV. The main objective was to characterize the current RHDV strains circulating in the studied area to help to choose an adequate vaccine. For that, we extracted viral RNA from rabbit livers, carried out the PCR analyses, and we sequenced the viral structural capsid protein (VP60) of the RHDV. The phylogenetic analysis results allowed us to state that the novel genotype (RHDV2) is circulating in the studied geographical area, and to characterize the isolated sequences. As a conclusion, we recommend updating RHD epidemiological relating data and reviewing the vaccine protocols by both targeting RHDV (GI.1) and RHDV2 (GI.2) in any future preventive program. |
| first_indexed | 2024-04-10T21:29:33Z |
| format | Article |
| id | doaj.art-6eb39411676248188d83d8b689641510 |
| institution | Directory Open Access Journal |
| issn | 1820-7448 |
| language | English |
| last_indexed | 2024-04-10T21:29:33Z |
| publishDate | 2022-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Veterinaria |
| spelling | doaj.art-6eb39411676248188d83d8b6896415102023-01-19T13:51:14ZengSciendoActa Veterinaria1820-74482022-12-0172443344110.2478/acve-2022-0035Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North AfricaSaidi Aissa0Aboutaib Abdelouahed1Regional Laboratory of Analyses and Research (ONSSA), Agadir80000, MoroccoVeterinary Practice (VMD), Oulad Teima83350, MoroccoRabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco. In addition to the classical virus (RHDV), a novel emerged genotype (RHDV2) is circulating, especially in the north shore of the Mediterranean basin since 2010. Many small animal farmers reported clinical cases from several rabbitries in Agadir (Morocco) despite systematic vaccination against the RHDV. The main objective was to characterize the current RHDV strains circulating in the studied area to help to choose an adequate vaccine. For that, we extracted viral RNA from rabbit livers, carried out the PCR analyses, and we sequenced the viral structural capsid protein (VP60) of the RHDV. The phylogenetic analysis results allowed us to state that the novel genotype (RHDV2) is circulating in the studied geographical area, and to characterize the isolated sequences. As a conclusion, we recommend updating RHD epidemiological relating data and reviewing the vaccine protocols by both targeting RHDV (GI.1) and RHDV2 (GI.2) in any future preventive program.https://doi.org/10.2478/acve-2022-0035rabbit hemorrhagic diseasemoroccorhdv2 (gi.2)vp60phylogeny |
| spellingShingle | Saidi Aissa Aboutaib Abdelouahed Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa Acta Veterinaria rabbit hemorrhagic disease morocco rhdv2 (gi.2) vp60 phylogeny |
| title | Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa |
| title_full | Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa |
| title_fullStr | Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa |
| title_full_unstemmed | Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa |
| title_short | Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa |
| title_sort | confirmation of the rabbit hemorrhagic disease virus type 2 gi 2 circulation in north africa |
| topic | rabbit hemorrhagic disease morocco rhdv2 (gi.2) vp60 phylogeny |
| url | https://doi.org/10.2478/acve-2022-0035 |
| work_keys_str_mv | AT saidiaissa confirmationoftherabbithemorrhagicdiseasevirustype2gi2circulationinnorthafrica AT aboutaibabdelouahed confirmationoftherabbithemorrhagicdiseasevirustype2gi2circulationinnorthafrica |