A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice

This study was conducted on 20 adult mice which were divided randomly in to 4 equal groups. The first group served as negative control (NC) that received the diluent (sun flower oil), while hyperlipidemia was induced in the other three groups, the second group received the diluent and considered as...

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Main Author: Lubna Ahmed Kafi
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2014-12-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/233
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author Lubna Ahmed Kafi
author_facet Lubna Ahmed Kafi
author_sort Lubna Ahmed Kafi
collection DOAJ
description This study was conducted on 20 adult mice which were divided randomly in to 4 equal groups. The first group served as negative control (NC) that received the diluent (sun flower oil), while hyperlipidemia was induced in the other three groups, the second group received the diluent and considered as positive control (PC), while group three and four were treated with olive oil (OO) or Nigella sativa oil (NSO) at a dose of 0.4ml/kg BW orally, respectively for two months. At the end of experiment and fasting overnight, lipid profile which included (total cholesterol TC, triglyceride TG, high density lipoprotein cholesterol HDL-C, low density lipoprotein cholesterol LDL-C and very low density lipoprotein cholesterol VLDL-C) were measured. The results indicated significant (P<0.05) improvement in all these parameters as compare to the positive control, while the value of HDL-C was significantly higher in the olive oil treated group as compared with all groups including negative control group.
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spelling doaj.art-6eb445b9d663450cb81a4e177ab3b3c52022-12-21T23:18:40ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092014-12-0138210.30539/iraqijvm.v38i2.233A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino miceLubna Ahmed Kafi0, College of Veterinary Medicine, University of BaghdadThis study was conducted on 20 adult mice which were divided randomly in to 4 equal groups. The first group served as negative control (NC) that received the diluent (sun flower oil), while hyperlipidemia was induced in the other three groups, the second group received the diluent and considered as positive control (PC), while group three and four were treated with olive oil (OO) or Nigella sativa oil (NSO) at a dose of 0.4ml/kg BW orally, respectively for two months. At the end of experiment and fasting overnight, lipid profile which included (total cholesterol TC, triglyceride TG, high density lipoprotein cholesterol HDL-C, low density lipoprotein cholesterol LDL-C and very low density lipoprotein cholesterol VLDL-C) were measured. The results indicated significant (P<0.05) improvement in all these parameters as compare to the positive control, while the value of HDL-C was significantly higher in the olive oil treated group as compared with all groups including negative control group.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/233hyperlipidemia, olive oil, Nigella sativa oil, mice
spellingShingle Lubna Ahmed Kafi
A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
The Iraqi Journal of Veterinary Medicine
hyperlipidemia, olive oil, Nigella sativa oil, mice
title A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
title_full A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
title_fullStr A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
title_full_unstemmed A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
title_short A comparative study between olive oil and Nigella Sativa oil in treatment of hyperlipidemia induced in male albino mice
title_sort comparative study between olive oil and nigella sativa oil in treatment of hyperlipidemia induced in male albino mice
topic hyperlipidemia, olive oil, Nigella sativa oil, mice
url https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/233
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AT lubnaahmedkafi comparativestudybetweenoliveoilandnigellasativaoilintreatmentofhyperlipidemiainducedinmalealbinomice