Mechanism for transmission and pathogenesis of carbapenem-resistant Enterobacterales harboring the carbapenemase IMP and clinical countermeasures

Mechanism for transmission and pathogenesis of carbapenem-resistant Enterobacterales harboring the carbapenemase IMP and clinical countermeasures

ABSTRACTCarbapenem-resistant Enterobacterales (CRE) are some of the most important pathogens causing infections, which can be challenging to treat. We identified four blaIMP-carrying CRE isolates and collected clinical data. The transferability and stability of the plasmid were verified by conjugati...

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Bibliographic Details
Main Authors: Chengru Yang, Shan Jiang, Chunli Wei, Chunjiang Li, Jianmin Wang, Xinhui Li, Lingyi Zeng, Kewang Hu, Yang Yang, Jisheng Zhang, Xiaoli Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
carbapenem-resistant Enterobacterales
IMP
traD
imipenem
tigecycline
bactericidal effect
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02318-23

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