CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease

CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease

Abstract Since its discovery in 2012, CRISPR Cas9 has been tried as a direct treatment approach to correct the causative gene mutation and establish animal models in neurodegenerative disorders. Since no strategy developed until now could completely cure Parkinson's disease (PD), neuroscientist...

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Bibliographic Details
Main Authors: Poojitha Pinjala, Kamatham Pushpa Tryphena, Renuka Prasad, Dharmendra Kumar Khatri, Woong Sun, Shashi Bala Singh, Dalapathi Gugulothu, Saurabh Srivastava, Lalitkumar Vora
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-05-01
Series:Biomaterials Research
Subjects:
Neurodegenerative disorder
α-synuclein
Gene editing
Human pluripotent stem cells
Embryonic stem cells
Disease model
Online Access:https://doi.org/10.1186/s40824-023-00381-y

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