Identification of microorganisms related to chronic rhinosinusitis in adult patients with variable common immunodeficiency

Background: The prevalence of chronic rhinosinusitis in adult patients with common variable immunodeficiency (CVID) is 52%. The patients with CVID show higher incidence of chronic rhinosinusitis, which is an inflammatory disease that affects the lining of one or more paranasal sinuses and nasal cavi...

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Bibliographic Details
Main Authors: Gabriela Angulo-Pérez, Eulalio Vivar-Acevedo, Diana Andrea Herrera-Sánchez
Format: Article
Language:English
Published: Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2016-03-01
Series:Revista Alergia México
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Online Access:http://revistaalergia.mx/ojs/index.php/ram/article/view/143
Description
Summary:Background: The prevalence of chronic rhinosinusitis in adult patients with common variable immunodeficiency (CVID) is 52%. The patients with CVID show higher incidence of chronic rhinosinusitis, which is an inflammatory disease that affects the lining of one or more paranasal sinuses and nasal cavity. Objective: To identify the microorganisms in the middle meatus secretion obtained by endoscopy associated with chronic rhinosinusitis in adult patients with common variable immunodeficiency (CVID). Material and method: A descriptive, cross-sectional study, which included adult patients with CVID, from whom a sample endoscopic middle meatus secretion from both nostrils was obtained and sent to culture for aerobic, anaerobic bacteria and fungi. Informed consent of all patients was obtained. Results: 29 patients were studied: 18 women and 11 men with a mean age of 40±13 years. The results were: 2 samples showed no microbial growth, 24 showed growth of aerobic bacteria, 3 cases had fungal growth without development of anaerobic bacteria. Conclusions: Our results show that the most common microorganisms associated with CSR in adult patients are: Moraxella catarrhalis, Staphylococcus, Sphingomonas paucimobilisand Citrobacter koseri, and associated fungal agents were: Candida albicans and Aspergillus fumigatus.
ISSN:0002-5151
2448-9190