Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis
Abstract The expression of the receptor tyrosine kinase Axl and its cleavage product soluble Axl (sAxl) is increased in liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). In this multicenter study, we evaluated the diagnostic value of Gas6, the high-affinity ligand of Axl, in patients wi...
Main Authors: | Katharina Staufer, Heidemarie Huber, Jasmin Zessner-Spitzenberg, Rudolf Stauber, Armin Finkenstedt, Heike Bantel, Thomas S. Weiss, Markus Huber, Patrick Starlinger, Thomas Gruenberger, Thomas Reiberger, Susanne Sebens, Gail McIntyre, Ray Tabibiazar, Amato Giaccia, Heinz Zoller, Michael Trauner, Wolfgang Mikulits |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01551-6 |
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