The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

Abstract The capture of tumour‐derived extracellular vesicles (TEVs) by cells in the tumour microenvironment (TME) contributes to metastasis and notably to the formation of the pre‐metastatic niche (PMN). However, due to the challenges associated with modelling release of small EVs in vivo, the kine...

Full description

Bibliographic Details
Main Authors: Laurence Blavier, Rie Nakata, Paolo Neviani, Khounish Sharma, Hiroyuki Shimada, Aitor Benedicto, Irina Matei, David Lyden, Yves A. DeClerck
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Journal of Extracellular Vesicles
Subjects:
exosomes
extracellular vesicles
inflammation
metastasis
microRNA
pre‐metastatic niche
Online Access:https://doi.org/10.1002/jev2.12326

Similar Items

Similar Items