Procoagulant Extracellular Vesicles Alter Trophoblast Differentiation in Mice by a Thrombo-Inflammatory Mechanism

Procoagulant Extracellular Vesicles Alter Trophoblast Differentiation in Mice by a Thrombo-Inflammatory Mechanism

Procoagulant extracellular vesicles (EV) and platelet activation have been associated with gestational vascular complications. EV-induced platelet-mediated placental inflammasome activation has been shown to cause preeclampsia-like symptoms in mice. However, the effect of EV-mediated placental throm...

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Bibliographic Details
Main Authors: Paulina Markmeyer, Franziska Lochmann, Kunal Kumar Singh, Anubhuti Gupta, Ruaa Younis, Khurrum Shahzad, Ronald Biemann, Hanna Huebner, Matthias Ruebner, Berend Isermann, Shrey Kohli
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
thrombo-inflammation
extracellular vesicles
inflammasome
trophoblast differentiation
Online Access:https://www.mdpi.com/1422-0067/22/18/9873

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