The Role of JAK/STAT Pathway in Fibrotic Diseases: Molecular and Cellular Mechanisms

The Role of JAK/STAT Pathway in Fibrotic Diseases: Molecular and Cellular Mechanisms

There are four members of the JAK family and seven of the STAT family in mammals. The JAK/STAT molecular pathway could be activated by broad hormones, cytokines, growth factors, and more. The JAK/STAT signaling pathway extensively mediates various biological processes such as cell proliferation, dif...

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Bibliographic Details
Main Authors: Jia Liu, Faping Wang, Fengming Luo
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
Janus kinases (JAK)
signal transducer and activator of transcription (STAT)
cytokines
fibrosis
fibroblast
inhibitor
Online Access:https://www.mdpi.com/2218-273X/13/1/119

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