Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1

Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1

In cervical cancer (CC), cisplatin resistance greatly restricts the application in clinical. Here, we report that engineered exosomes-mediated transfer of hsa-miR-320a overcomes chemoresistance in cervical cancer cells via targeting Myeloid Cell Leukemia Sequence 1 (MCL1). In DDP resistant CC tissue...

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Bibliographic Details
Main Authors: Jinling Zhou, Yuanhe Wang, Lizhu Zhang, Qin Chen, Xiaojun Zhu, Peiyue Jiang, Nan Jiang, Wei Zhao, Baohua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
engineered exosomes
cervical cancer
has-miR-320a
Mcl1
chemoresistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.883445/full

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