Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase.
Pericentric heterochromatin, while often considered as "junk" DNA, plays important functions in chromosome biology. It contributes to sister chromatid cohesion, a process mediated by the cohesin complex that ensures proper genome segregation during nuclear division. Long stretches of heter...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-10-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4188515?pdf=render |