The Functional Network of the Visual Cortex Is Altered in Migraine
Migraine is a common neurological disorder characterized by recurrent episodes of headache, frequently accompanied by various reversible neurological disturbances. Some migraine patients experience visually triggered migraine headache, and most attacks of migraine with aura are associated with the d...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Vision |
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| Online Access: | https://www.mdpi.com/2411-5150/5/4/57 |
| _version_ | 1797499907052929024 |
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| author | Jie Huang Arnold Wilkins |
| author_facet | Jie Huang Arnold Wilkins |
| author_sort | Jie Huang |
| collection | DOAJ |
| description | Migraine is a common neurological disorder characterized by recurrent episodes of headache, frequently accompanied by various reversible neurological disturbances. Some migraine patients experience visually triggered migraine headache, and most attacks of migraine with aura are associated with the disturbance of vision and photophobia, suggesting an abnormal neural activity in the visual cortex. Numerous studies have shown a large cortical hemodynamic response to visual stimulation and an altered intrinsic visual functional connectivity network in patients with migraine. In this interictal study, we applied a novel data-driven method with fMRI to identify the functional network in the visual cortex evoked by visual stimulation and investigated the effect of migraine on this network. We found that the distribution of the functional network along both the ventral and dorsal visual pathways differed between migraine patients and non-headache healthy control participants, providing evidence that the functional network was altered in migraine between headaches. The functional network was bilateral in the control participants but substantially lateralized in the migraine patients. The results also indicated different effects of colored lenses on the functional network for both participant groups. |
| first_indexed | 2024-03-10T03:54:11Z |
| format | Article |
| id | doaj.art-6ed5769226c544b69fa5e2532e0d3282 |
| institution | Directory Open Access Journal |
| issn | 2411-5150 |
| language | English |
| last_indexed | 2024-03-10T03:54:11Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vision |
| spelling | doaj.art-6ed5769226c544b69fa5e2532e0d32822023-11-23T10:59:48ZengMDPI AGVision2411-51502021-11-01545710.3390/vision5040057The Functional Network of the Visual Cortex Is Altered in MigraineJie Huang0Arnold Wilkins1Department of Radiology, Michigan State University, East Lansing, MI 48824, USADepartment of Psychology, University of Essex, Colchester CO4 3SQ, UKMigraine is a common neurological disorder characterized by recurrent episodes of headache, frequently accompanied by various reversible neurological disturbances. Some migraine patients experience visually triggered migraine headache, and most attacks of migraine with aura are associated with the disturbance of vision and photophobia, suggesting an abnormal neural activity in the visual cortex. Numerous studies have shown a large cortical hemodynamic response to visual stimulation and an altered intrinsic visual functional connectivity network in patients with migraine. In this interictal study, we applied a novel data-driven method with fMRI to identify the functional network in the visual cortex evoked by visual stimulation and investigated the effect of migraine on this network. We found that the distribution of the functional network along both the ventral and dorsal visual pathways differed between migraine patients and non-headache healthy control participants, providing evidence that the functional network was altered in migraine between headaches. The functional network was bilateral in the control participants but substantially lateralized in the migraine patients. The results also indicated different effects of colored lenses on the functional network for both participant groups.https://www.mdpi.com/2411-5150/5/4/57migrainemigraine aurafMRIFAUPAvisual cortical functional network |
| spellingShingle | Jie Huang Arnold Wilkins The Functional Network of the Visual Cortex Is Altered in Migraine Vision migraine migraine aura fMRI FAUPA visual cortical functional network |
| title | The Functional Network of the Visual Cortex Is Altered in Migraine |
| title_full | The Functional Network of the Visual Cortex Is Altered in Migraine |
| title_fullStr | The Functional Network of the Visual Cortex Is Altered in Migraine |
| title_full_unstemmed | The Functional Network of the Visual Cortex Is Altered in Migraine |
| title_short | The Functional Network of the Visual Cortex Is Altered in Migraine |
| title_sort | functional network of the visual cortex is altered in migraine |
| topic | migraine migraine aura fMRI FAUPA visual cortical functional network |
| url | https://www.mdpi.com/2411-5150/5/4/57 |
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