Oxidative Stress Mediates Epigenetic Modifications and the Expression of miRNAs and Genes Related to Apoptosis in Diabetic Retinopathy Patients

Oxidative Stress Mediates Epigenetic Modifications and the Expression of miRNAs and Genes Related to Apoptosis in Diabetic Retinopathy Patients

Knowledge on the underlying mechanisms and molecular targets for managing the ocular complications of type 2 diabetes mellitus (T2DM) remains incomplete. Diabetic retinopathy (DR) is a major cause of irreversible visual disability worldwide. By using ophthalmological and molecular-genetic approaches...

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Bibliographic Details
Main Authors: Sarah Karam-Palos, Irene Andrés-Blasco, Cristina Campos-Borges, Vicente Zanón-Moreno, Alex Gallego-Martínez, Victor Alegre-Ituarte, Jose J. García-Medina, Salvador Pastor-Idoate, Inmaculada Sellés-Navarro, Jorge Vila-Arteaga, Antonio V. Lleó-Perez, Maria D. Pinazo-Durán
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Clinical Medicine
Subjects:
diabetic retinopathy
oxidative stress
microRNAs
genes
apoptosis
epigenetics
Online Access:https://www.mdpi.com/2077-0383/13/1/74

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