6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion
MotivationThe biological function of N6-methyladenine DNA (6mA) in plants is largely unknown. Rice is one of the most important crops worldwide and is a model species for molecular and genetic studies. There are few methods for 6mA site recognition in the rice genome, and an effective computational...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-01-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpls.2020.00004/full |
| _version_ | 1819043167510462464 |
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| author | Qianfei Huang Jun Zhang Leyi Wei Fei Guo Quan Zou |
| author_facet | Qianfei Huang Jun Zhang Leyi Wei Fei Guo Quan Zou |
| author_sort | Qianfei Huang |
| collection | DOAJ |
| description | MotivationThe biological function of N6-methyladenine DNA (6mA) in plants is largely unknown. Rice is one of the most important crops worldwide and is a model species for molecular and genetic studies. There are few methods for 6mA site recognition in the rice genome, and an effective computational method is needed.ResultsIn this paper, we propose a new computational method called 6mA-Pred to identify 6mA sites in the rice genome. 6mA-Pred employs a feature fusion method to combine advantageous features from other methods and thus obtain a new feature to identify 6mA sites. This method achieved an accuracy of 87.27% in the identification of 6mA sites with 10-fold cross-validation and achieved an accuracy of 85.6% in independent test sets. |
| first_indexed | 2024-12-21T09:52:29Z |
| format | Article |
| id | doaj.art-6edc5db494914e25b333556e297026ca |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-21T09:52:29Z |
| publishDate | 2020-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-6edc5db494914e25b333556e297026ca2022-12-21T19:08:10ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2020-01-011110.3389/fpls.2020.000045140896mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature FusionQianfei Huang0Jun Zhang1Leyi Wei2Fei Guo3Quan Zou4College of Intelligence and Computing, Tianjin University, Tianjin, ChinaRehabilitation Department, Heilongjiang Province Land Reclamation Headquarters General Hospital, Harbin, ChinaCollege of Intelligence and Computing, Tianjin University, Tianjin, ChinaCollege of Intelligence and Computing, Tianjin University, Tianjin, ChinaInstitute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, ChinaMotivationThe biological function of N6-methyladenine DNA (6mA) in plants is largely unknown. Rice is one of the most important crops worldwide and is a model species for molecular and genetic studies. There are few methods for 6mA site recognition in the rice genome, and an effective computational method is needed.ResultsIn this paper, we propose a new computational method called 6mA-Pred to identify 6mA sites in the rice genome. 6mA-Pred employs a feature fusion method to combine advantageous features from other methods and thus obtain a new feature to identify 6mA sites. This method achieved an accuracy of 87.27% in the identification of 6mA sites with 10-fold cross-validation and achieved an accuracy of 85.6% in independent test sets.https://www.frontiersin.org/article/10.3389/fpls.2020.00004/fullricemodelfusionDNA6mA |
| spellingShingle | Qianfei Huang Jun Zhang Leyi Wei Fei Guo Quan Zou 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion Frontiers in Plant Science rice model fusion DNA 6mA |
| title | 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion |
| title_full | 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion |
| title_fullStr | 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion |
| title_full_unstemmed | 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion |
| title_short | 6mA-RicePred: A Method for Identifying DNA N6-Methyladenine Sites in the Rice Genome Based on Feature Fusion |
| title_sort | 6ma ricepred a method for identifying dna n6 methyladenine sites in the rice genome based on feature fusion |
| topic | rice model fusion DNA 6mA |
| url | https://www.frontiersin.org/article/10.3389/fpls.2020.00004/full |
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