Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA

Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA

Cas7-11 is a Type III-E CRISPR Cas effector that confers programmable RNA cleavage and has potential applications in RNA interference. Cas7-11 encodes a single polypeptide containing four Cas7- and one Cas11-like segments that obscures the distinction between the multi-subunit Class 1 and the single...

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Bibliographic Details
Main Authors: Hemant N Goswami, Jay Rai, Anuska Das, Hong Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
CRISPR Type III-E
CRISPR Cas7-11
programmable RNA cleavage
CRISPR gRAMP
TPR-CHAT peptidase
Online Access:https://elifesciences.org/articles/81678

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