Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report docum...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/2/464 |
| _version_ | 1827756809254862848 |
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| author | Timothy C. Frommeyer Tongfan Wu Michael M. Gilbert Garrett V. Brittain Stephen P. Fuqua |
| author_facet | Timothy C. Frommeyer Tongfan Wu Michael M. Gilbert Garrett V. Brittain Stephen P. Fuqua |
| author_sort | Timothy C. Frommeyer |
| collection | DOAJ |
| description | Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report documents a case of CVST in a 32-year-old female patient who received her second Pfizer mRNA COVID-19 vaccination 16 days prior to hospital admission and had started oral combined contraceptives approximately 4 months beforehand. Clinicians should be cognizant of the possibility that mRNA vaccines, when combined with other risk factors like oral contraceptive pill use, may enhance one’s hypercoagulable status. |
| first_indexed | 2024-03-11T08:32:29Z |
| format | Article |
| id | doaj.art-6eeb29c795d141ecbe7532be0f9ce8c5 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T08:32:29Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-6eeb29c795d141ecbe7532be0f9ce8c52023-11-16T21:41:37ZengMDPI AGLife2075-17292023-02-0113246410.3390/life13020464Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive UseTimothy C. Frommeyer0Tongfan Wu1Michael M. Gilbert2Garrett V. Brittain3Stephen P. Fuqua4Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USADepartment of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USADepartment of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USADepartment of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USADepartment of Neurology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435, USARising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report documents a case of CVST in a 32-year-old female patient who received her second Pfizer mRNA COVID-19 vaccination 16 days prior to hospital admission and had started oral combined contraceptives approximately 4 months beforehand. Clinicians should be cognizant of the possibility that mRNA vaccines, when combined with other risk factors like oral contraceptive pill use, may enhance one’s hypercoagulable status.https://www.mdpi.com/2075-1729/13/2/464cerebral venous thrombosisCOVID-19vaccinationoral contraceptionmRNA |
| spellingShingle | Timothy C. Frommeyer Tongfan Wu Michael M. Gilbert Garrett V. Brittain Stephen P. Fuqua Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use Life cerebral venous thrombosis COVID-19 vaccination oral contraception mRNA |
| title | Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use |
| title_full | Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use |
| title_fullStr | Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use |
| title_full_unstemmed | Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use |
| title_short | Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use |
| title_sort | cerebral venous sinus thrombosis following an mrna covid 19 vaccination and recent oral contraceptive use |
| topic | cerebral venous thrombosis COVID-19 vaccination oral contraception mRNA |
| url | https://www.mdpi.com/2075-1729/13/2/464 |
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