Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders
Abstract.: Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer’s disease, Parkinson’s disease, stroke, amyotrophic lateral sclerosis, and Huntington’s disease that have no effective treatment available to date. The adipose-deriv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-04-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319300878 |
| _version_ | 1818153384743534592 |
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| author | Keun-A Chang Jun-Ho Lee Yoo-Hun Suh |
| author_facet | Keun-A Chang Jun-Ho Lee Yoo-Hun Suh |
| author_sort | Keun-A Chang |
| collection | DOAJ |
| description | Abstract.: Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer’s disease, Parkinson’s disease, stroke, amyotrophic lateral sclerosis, and Huntington’s disease that have no effective treatment available to date. The adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency with the ability to differentiate into various types of cells and immuno-modulatory property. These biological features make ASCs a promising source for regenerative cell therapy in neurological disorders. Here we discuss the recent progress of regenerative therapies in various neurological disorders utilizing ASCs. Keywords:: neurological disorder, adipose-derived stem cell (ASC), Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) |
| first_indexed | 2024-12-11T14:09:46Z |
| format | Article |
| id | doaj.art-6eee817f15994e64916c3ed94fc2248c |
| institution | Directory Open Access Journal |
| issn | 1347-8613 |
| language | English |
| last_indexed | 2024-12-11T14:09:46Z |
| publishDate | 2014-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pharmacological Sciences |
| spelling | doaj.art-6eee817f15994e64916c3ed94fc2248c2022-12-22T01:03:29ZengElsevierJournal of Pharmacological Sciences1347-86132014-04-011264293301Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological DisordersKeun-A Chang0Jun-Ho Lee1Yoo-Hun Suh2Department of Pharmacology, College of Medicine, Neuroscience Research Institute, Gachon University, Incheon 405-760, KoreaDepartment of Emergency Medical Technology, College of Natural Science, Daejeon University, Daejeon 300-716, KoreaKorea Brain Research Institute (KBRI), 425 Jungang-daero, Jung-gu, Daegu 700-010, Korea; Corresponding author. yhsuh@kbri.re.krAbstract.: Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer’s disease, Parkinson’s disease, stroke, amyotrophic lateral sclerosis, and Huntington’s disease that have no effective treatment available to date. The adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency with the ability to differentiate into various types of cells and immuno-modulatory property. These biological features make ASCs a promising source for regenerative cell therapy in neurological disorders. Here we discuss the recent progress of regenerative therapies in various neurological disorders utilizing ASCs. Keywords:: neurological disorder, adipose-derived stem cell (ASC), Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD)http://www.sciencedirect.com/science/article/pii/S1347861319300878 |
| spellingShingle | Keun-A Chang Jun-Ho Lee Yoo-Hun Suh Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders Journal of Pharmacological Sciences |
| title | Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders |
| title_full | Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders |
| title_fullStr | Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders |
| title_full_unstemmed | Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders |
| title_short | Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders |
| title_sort | therapeutic potential of human adipose derived stem cells in neurological disorders |
| url | http://www.sciencedirect.com/science/article/pii/S1347861319300878 |
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