Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis
AIM: To investigate the characteristics of changes in corneal epithelial thickness at the early postoperative stage of femtosecond assisted laser in situ keratomileusis(FS-LASIK)and its related influencing factors.METHOD: Retrospective study. A total of 120 patients(240 eyes)of myopia undergoing FS-...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2023-09-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2023/9/202309025.pdf |
| _version_ | 1797739551291080704 |
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| author | Yang Xu Xiao-Guang Niu Li Liu Shu-Juan Wu Xiao-Yang He |
| author_facet | Yang Xu Xiao-Guang Niu Li Liu Shu-Juan Wu Xiao-Yang He |
| author_sort | Yang Xu |
| collection | DOAJ |
| description | AIM: To investigate the characteristics of changes in corneal epithelial thickness at the early postoperative stage of femtosecond assisted laser in situ keratomileusis(FS-LASIK)and its related influencing factors.METHOD: Retrospective study. A total of 120 patients(240 eyes)of myopia undergoing FS-LASIK from May 2021 to June 2022 were selected. The corneal epithelium thickness in the central area, inner ring area, and outer ring area of patients before and at 1d, 1wk, 1 and 3mo after operation was recorded. The relationship between the variation of corneal epithelium thickness and spherical equivalent, optical zone diameter, depth of cut and cutting ratio was analyzed by Pearson correlation.RESULTS: There was no statistical significance in corneal epithelial thickness in the central area, inner ring area and outer ring area at 1d after FS-LASIK compared with that before operation(P>0.05). At 1wk, 1 and 3mo after surgery, the corneal epithelial thickness in the central area, inner ring area and outer ring area increased compared with that before surgery, and the corneal epithelial thickness in the central area and inner ring area at 1 and 3mo after surgery was greater than that in the outer ring area(all P<0.05). The corneal epithelial thickness in the central, inner and outer ring areas of high myopia patients was thicker than that of low and moderate myopia patients before operation. The corneal epithelial thickness in the central, inner and outer ring areas of high myopia patients was thinner than that of low and moderate myopia patients at 1wk after operation(P<0.05). At 1 and 3mo after operation, the corneal epithelial thickness in the central, inner and outer ring areas of patients with high myopia was greater than that of patients with low and moderate myopia, and the changes of corneal epithelial thickness in the central, inner and outer ring areas were greater than those of patients with low and moderate myopia(P<0.05). The results of Pearson correlation showed that the changes in corneal epithelial thickness in the central and inner ring area were positively correlated with the corneal curvature, depth of cut and cutting ratio at 3mo after surgery, and they were in negative correlation with the age, spherical equivalent and optical zone diameter(P<0.05).CONCLUSION: The corneal epithelial thickness of patients thickened after the FS-LASIK operation, and it was correlated with age, corneal curvature, preoperative depth of cut, cutting ratio, spherical equivalent and the optic zone diameter. |
| first_indexed | 2024-03-12T13:59:49Z |
| format | Article |
| id | doaj.art-6eeef9ae02f3468cb374e7634c01bb54 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-12T13:59:49Z |
| publishDate | 2023-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-6eeef9ae02f3468cb374e7634c01bb542023-08-22T08:49:53ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232023-09-012391550155410.3980/j.issn.1672-5123.2023.9.25202309025Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusisYang Xu0Xiao-Guang Niu1Li Liu2Shu-Juan Wu3Xiao-Yang He4Department of Refractive, Wuhan Aier Eye Hanyang Hospital, Wuhan 430050, Hubei Province, ChinaDepartment of Refractive, Wuhan Aier Eye Hanyang Hospital, Wuhan 430050, Hubei Province, ChinaDepartment of Refractive, Wuhan Aier Eye Hanyang Hospital, Wuhan 430050, Hubei Province, ChinaDepartment of Refractive, Wuhan Aier Eye Hanyang Hospital, Wuhan 430050, Hubei Province, ChinaDepartment of Refractive, Wuhan Aier Eye Hanyang Hospital, Wuhan 430050, Hubei Province, ChinaAIM: To investigate the characteristics of changes in corneal epithelial thickness at the early postoperative stage of femtosecond assisted laser in situ keratomileusis(FS-LASIK)and its related influencing factors.METHOD: Retrospective study. A total of 120 patients(240 eyes)of myopia undergoing FS-LASIK from May 2021 to June 2022 were selected. The corneal epithelium thickness in the central area, inner ring area, and outer ring area of patients before and at 1d, 1wk, 1 and 3mo after operation was recorded. The relationship between the variation of corneal epithelium thickness and spherical equivalent, optical zone diameter, depth of cut and cutting ratio was analyzed by Pearson correlation.RESULTS: There was no statistical significance in corneal epithelial thickness in the central area, inner ring area and outer ring area at 1d after FS-LASIK compared with that before operation(P>0.05). At 1wk, 1 and 3mo after surgery, the corneal epithelial thickness in the central area, inner ring area and outer ring area increased compared with that before surgery, and the corneal epithelial thickness in the central area and inner ring area at 1 and 3mo after surgery was greater than that in the outer ring area(all P<0.05). The corneal epithelial thickness in the central, inner and outer ring areas of high myopia patients was thicker than that of low and moderate myopia patients before operation. The corneal epithelial thickness in the central, inner and outer ring areas of high myopia patients was thinner than that of low and moderate myopia patients at 1wk after operation(P<0.05). At 1 and 3mo after operation, the corneal epithelial thickness in the central, inner and outer ring areas of patients with high myopia was greater than that of patients with low and moderate myopia, and the changes of corneal epithelial thickness in the central, inner and outer ring areas were greater than those of patients with low and moderate myopia(P<0.05). The results of Pearson correlation showed that the changes in corneal epithelial thickness in the central and inner ring area were positively correlated with the corneal curvature, depth of cut and cutting ratio at 3mo after surgery, and they were in negative correlation with the age, spherical equivalent and optical zone diameter(P<0.05).CONCLUSION: The corneal epithelial thickness of patients thickened after the FS-LASIK operation, and it was correlated with age, corneal curvature, preoperative depth of cut, cutting ratio, spherical equivalent and the optic zone diameter.http://ies.ijo.cn/cn_publish/2023/9/202309025.pdfmyopiafemtosecond assisted laser in situ keratomileusiscorneal epithelial thicknessinfluencing factor |
| spellingShingle | Yang Xu Xiao-Guang Niu Li Liu Shu-Juan Wu Xiao-Yang He Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis Guoji Yanke Zazhi myopia femtosecond assisted laser in situ keratomileusis corneal epithelial thickness influencing factor |
| title | Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| title_full | Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| title_fullStr | Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| title_full_unstemmed | Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| title_short | Characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| title_sort | characteristics of early changes in corneal epithelial thickness and related influencing factors after femtosecond assisted laser in situ keratomileusis |
| topic | myopia femtosecond assisted laser in situ keratomileusis corneal epithelial thickness influencing factor |
| url | http://ies.ijo.cn/cn_publish/2023/9/202309025.pdf |
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