The role of radiotherapy in urinary bladder cancer: current status
The role of radiotherapy (RT) in the treatment of urinary bladder cancer has undergone several modifications along the last decades. In the beginning, definitive RT was used as treatment in an attempt to preserve the urinary bladder; however, the results were poor compared to those of radical surger...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Urologia
2012-04-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382012000200002 |
| _version_ | 1819212838569246720 |
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| author | Gustavo Nader Marta Samir Abdallah Hanna Rafael Gadia Sebastião Francisco Miranda Correa Joao Luis Fernandes da Silva Heloisa de Andrade Carvalho |
| author_facet | Gustavo Nader Marta Samir Abdallah Hanna Rafael Gadia Sebastião Francisco Miranda Correa Joao Luis Fernandes da Silva Heloisa de Andrade Carvalho |
| author_sort | Gustavo Nader Marta |
| collection | DOAJ |
| description | The role of radiotherapy (RT) in the treatment of urinary bladder cancer has undergone several modifications along the last decades. In the beginning, definitive RT was used as treatment in an attempt to preserve the urinary bladder; however, the results were poor compared to those of radical surgery. Recently, many protocols have been developed supporting the use of multi-modality therapy, and the concept of organ preservation began to be reconsidered. Although phase III randomized clinical studies comparing radical cystectomy with bladder preservation therapies do not exist, the conservative treatment may present low toxicity and high indexes of complete response for selected patients. The aim of this study was to review the literature on the subject in order to situate RT in the current treatment of urinary bladder cancer. |
| first_indexed | 2024-12-23T06:49:20Z |
| format | Article |
| id | doaj.art-6ef04b9137ba4f91b6d258521b3ba021 |
| institution | Directory Open Access Journal |
| issn | 1677-5538 1677-6119 |
| language | English |
| last_indexed | 2024-12-23T06:49:20Z |
| publishDate | 2012-04-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-6ef04b9137ba4f91b6d258521b3ba0212022-12-21T17:56:28ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192012-04-0138214415610.1590/S1677-55382012000200002The role of radiotherapy in urinary bladder cancer: current statusGustavo Nader MartaSamir Abdallah HannaRafael GadiaSebastião Francisco Miranda CorreaJoao Luis Fernandes da SilvaHeloisa de Andrade CarvalhoThe role of radiotherapy (RT) in the treatment of urinary bladder cancer has undergone several modifications along the last decades. In the beginning, definitive RT was used as treatment in an attempt to preserve the urinary bladder; however, the results were poor compared to those of radical surgery. Recently, many protocols have been developed supporting the use of multi-modality therapy, and the concept of organ preservation began to be reconsidered. Although phase III randomized clinical studies comparing radical cystectomy with bladder preservation therapies do not exist, the conservative treatment may present low toxicity and high indexes of complete response for selected patients. The aim of this study was to review the literature on the subject in order to situate RT in the current treatment of urinary bladder cancer.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382012000200002radiotherapyurinary bladderneoplasmsreview |
| spellingShingle | Gustavo Nader Marta Samir Abdallah Hanna Rafael Gadia Sebastião Francisco Miranda Correa Joao Luis Fernandes da Silva Heloisa de Andrade Carvalho The role of radiotherapy in urinary bladder cancer: current status International Brazilian Journal of Urology radiotherapy urinary bladder neoplasms review |
| title | The role of radiotherapy in urinary bladder cancer: current status |
| title_full | The role of radiotherapy in urinary bladder cancer: current status |
| title_fullStr | The role of radiotherapy in urinary bladder cancer: current status |
| title_full_unstemmed | The role of radiotherapy in urinary bladder cancer: current status |
| title_short | The role of radiotherapy in urinary bladder cancer: current status |
| title_sort | role of radiotherapy in urinary bladder cancer current status |
| topic | radiotherapy urinary bladder neoplasms review |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382012000200002 |
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