Global epidemiology of celiac disease

The review presents the data on the prevalence of celiac disease in various world regions. The numbers of patients with celiac disease continues to rise every year. According to some authors, this is to be related not only to improvement in diagnosis, but to other extrinsic factors, as well, that re...

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Main Authors: S. V. Bykova, A. I. Parfenov, E. A. Sabel'nikova
Format: Article
Language:Russian
Published: MONIKI 2018-04-01
Series:Alʹmanah Kliničeskoj Mediciny
Subjects:
Online Access:https://www.almclinmed.ru/jour/article/view/753
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author S. V. Bykova
A. I. Parfenov
E. A. Sabel'nikova
author_facet S. V. Bykova
A. I. Parfenov
E. A. Sabel'nikova
author_sort S. V. Bykova
collection DOAJ
description The review presents the data on the prevalence of celiac disease in various world regions. The numbers of patients with celiac disease continues to rise every year. According to some authors, this is to be related not only to improvement in diagnosis, but to other extrinsic factors, as well, that require additional studies. In the 1980s the prevalence of this disease was 1.05%, and by the beginning of 2000s, it amounted to 1.99%. In particular, from 1993 to 2002 in Britain its incidence increased from 6 to 13.3 per 100,000. Both raised awareness of doctors and conduction of epidemiological studies play a decisive role in the improvement of the diagnosis of celiac disease. The information cumulated up to now makes it possible to conclude that the highest diagnostic rates of celiac disease can be found in the risk groups. They include 1st and 2nd degree relatives of patients with celiac disease, patients with autoimmune disorders (type 1 diabetes mellitus, autoimmune thyroiditis); those with clinical signs of an intestinal disorder, such as chronic diarrhea, as well as patients with anemia, osteoporosis and high transaminase levels of unknown origin. According to the Finnish epidemiological study, the prevalence of celiac disease, depending on the risk group, may vary from 6.6 to 16.3%. The guidelines by the American College of Gastroenterology, British Society of Gastroenterology, North-American Society of Pediatric Gastroenterology, and the Russian Consensus on Diagnosis and Treatment of Celiac Disease in Adults and Children all recommend thorough examination of patients from the risk groups. Active diagnosis of celiac disease (screening) has been recognized as one of the approaches to primary prevention to autoimmune disorders and cancer.
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spelling doaj.art-6ef07794d67d43868f112cd326ad024f2022-12-21T18:47:42ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942018-04-01461233110.18786/2072-0505-2018-46-1-23-31509Global epidemiology of celiac diseaseS. V. Bykova0A. I. Parfenov1E. A. Sabel'nikova2Loginov Moscow Clinical Scientific Center, Moscow Healthcare DepartmentLoginov Moscow Clinical Scientific Center, Moscow Healthcare DepartmentLoginov Moscow Clinical Scientific Center, Moscow Healthcare DepartmentThe review presents the data on the prevalence of celiac disease in various world regions. The numbers of patients with celiac disease continues to rise every year. According to some authors, this is to be related not only to improvement in diagnosis, but to other extrinsic factors, as well, that require additional studies. In the 1980s the prevalence of this disease was 1.05%, and by the beginning of 2000s, it amounted to 1.99%. In particular, from 1993 to 2002 in Britain its incidence increased from 6 to 13.3 per 100,000. Both raised awareness of doctors and conduction of epidemiological studies play a decisive role in the improvement of the diagnosis of celiac disease. The information cumulated up to now makes it possible to conclude that the highest diagnostic rates of celiac disease can be found in the risk groups. They include 1st and 2nd degree relatives of patients with celiac disease, patients with autoimmune disorders (type 1 diabetes mellitus, autoimmune thyroiditis); those with clinical signs of an intestinal disorder, such as chronic diarrhea, as well as patients with anemia, osteoporosis and high transaminase levels of unknown origin. According to the Finnish epidemiological study, the prevalence of celiac disease, depending on the risk group, may vary from 6.6 to 16.3%. The guidelines by the American College of Gastroenterology, British Society of Gastroenterology, North-American Society of Pediatric Gastroenterology, and the Russian Consensus on Diagnosis and Treatment of Celiac Disease in Adults and Children all recommend thorough examination of patients from the risk groups. Active diagnosis of celiac disease (screening) has been recognized as one of the approaches to primary prevention to autoimmune disorders and cancer.https://www.almclinmed.ru/jour/article/view/753celiac diseaseprevalenceautoimmune disorderscreening
spellingShingle S. V. Bykova
A. I. Parfenov
E. A. Sabel'nikova
Global epidemiology of celiac disease
Alʹmanah Kliničeskoj Mediciny
celiac disease
prevalence
autoimmune disorder
screening
title Global epidemiology of celiac disease
title_full Global epidemiology of celiac disease
title_fullStr Global epidemiology of celiac disease
title_full_unstemmed Global epidemiology of celiac disease
title_short Global epidemiology of celiac disease
title_sort global epidemiology of celiac disease
topic celiac disease
prevalence
autoimmune disorder
screening
url https://www.almclinmed.ru/jour/article/view/753
work_keys_str_mv AT svbykova globalepidemiologyofceliacdisease
AT aiparfenov globalepidemiologyofceliacdisease
AT easabelnikova globalepidemiologyofceliacdisease