Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients

Abstract Schizophrenia is a heterogeneous psychiatric disorder with a strong genetic basis, whose etiology and pathophysiology remain poorly understood. Exome sequencing studies have uncovered rare, loss-of-function variants that greatly increase risk of schizophrenia [1], including loss-of-function...

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Bibliographic Details
Main Authors: Linnea E. Herzog, Lei Wang, Eunah Yu, Soonwook Choi, Zohreh Farsi, Bryan J. Song, Jen Q. Pan, Morgan Sheng
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02393-7

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