P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS
Aortic stiffness is associated to chronic kidney disease. Although it is well established that patients with chronic kidney disease have classical and non classical risk factors correlated to a high pulse wave velocity, there is no data on the deleterious effect of high pulse wave velocity on intra...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2015-11-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125930665/view |
| _version_ | 1818006342761185280 |
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| author | Rania Kheder-Elfekih* Hela Jebali Lamia Rais Fatma Ben Moussa Karim Zouaghi |
| author_facet | Rania Kheder-Elfekih* Hela Jebali Lamia Rais Fatma Ben Moussa Karim Zouaghi |
| author_sort | Rania Kheder-Elfekih* |
| collection | DOAJ |
| description | Aortic stiffness is associated to chronic kidney disease. Although it is well established that patients with chronic kidney disease have classical and non classical risk factors correlated to a high pulse wave velocity, there is no data on the deleterious effect of high pulse wave velocity on intra renal microvasculature.
The aim of this study was to explore the relationship between arterial stiffness, assessed by cfPWV and renal microvascular lesions assessed by renal biopsy.
In 25 patients who went through a renal biopsy we analysed renal vascular lesions, and obtained cfPWV using a Complior device.
cfPWV and age were positively correlated to the severity of vascular lesions.
These results support the hypoyhesis that an elevated pulsatility in target organ microcirculation such as kidneys leads to vessel damage and contributes to worsen glomerular filtration rate. |
| first_indexed | 2024-04-14T04:59:42Z |
| format | Article |
| id | doaj.art-6ef58230c3bf41258bf8984de9f0bcb7 |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-04-14T04:59:42Z |
| publishDate | 2015-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-6ef58230c3bf41258bf8984de9f0bcb72022-12-22T02:11:00ZengBMCArtery Research1876-44012015-11-011210.1016/j.artres.2015.10.326P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONSRania Kheder-Elfekih*Hela JebaliLamia RaisFatma Ben MoussaKarim ZouaghiAortic stiffness is associated to chronic kidney disease. Although it is well established that patients with chronic kidney disease have classical and non classical risk factors correlated to a high pulse wave velocity, there is no data on the deleterious effect of high pulse wave velocity on intra renal microvasculature. The aim of this study was to explore the relationship between arterial stiffness, assessed by cfPWV and renal microvascular lesions assessed by renal biopsy. In 25 patients who went through a renal biopsy we analysed renal vascular lesions, and obtained cfPWV using a Complior device. cfPWV and age were positively correlated to the severity of vascular lesions. These results support the hypoyhesis that an elevated pulsatility in target organ microcirculation such as kidneys leads to vessel damage and contributes to worsen glomerular filtration rate.https://www.atlantis-press.com/article/125930665/view |
| spellingShingle | Rania Kheder-Elfekih* Hela Jebali Lamia Rais Fatma Ben Moussa Karim Zouaghi P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS Artery Research |
| title | P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS |
| title_full | P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS |
| title_fullStr | P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS |
| title_full_unstemmed | P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS |
| title_short | P8.3 RELATIONSHIP BETWEEN PULSE WAVE VELOCITY AND BIOPSY PROVEN RENAL MICROVASCULAR LESIONS |
| title_sort | p8 3 relationship between pulse wave velocity and biopsy proven renal microvascular lesions |
| url | https://www.atlantis-press.com/article/125930665/view |
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