Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease
Aldehyde dehydrogenase 2 (ALDH2) is an enzyme found in the mitochondrial matrix that plays a central role in alcohol and aldehyde metabolism. A common ALDH2 polymorphism in East Asians descent (called ALDH2*2 or E504K missense variant, SNP ID: rs671), present in approximately 8% of the world’s popul...
Main Authors: | Takuya Seike, Che-Hong Chen, Daria Mochly-Rosen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1223977/full |
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