Differentiation of Pancreatic lesions using Diffusion-Weighted MRI

The purpose of this study was to evaluate the role of diffusion-weighted imaging (DWI) in diagnosis of pancreatic lesions, to compare diagnostic accuracy of conventional MRI (MRI-c), DWI and diffusion coefficient (ADC) values of lesions. Patient and methods: Thirty-six patients with pancreatic lesio...

Full description

Bibliographic Details
Main Authors: Mohamad Hamid Abo Warda, Doaa Ibrahim Hasan, Osama Abdelaziz Elteeh
Format: Article
Language:English
Published: SpringerOpen 2015-09-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0378603X15000662
_version_ 1818947934573559808
author Mohamad Hamid Abo Warda
Doaa Ibrahim Hasan
Osama Abdelaziz Elteeh
author_facet Mohamad Hamid Abo Warda
Doaa Ibrahim Hasan
Osama Abdelaziz Elteeh
author_sort Mohamad Hamid Abo Warda
collection DOAJ
description The purpose of this study was to evaluate the role of diffusion-weighted imaging (DWI) in diagnosis of pancreatic lesions, to compare diagnostic accuracy of conventional MRI (MRI-c), DWI and diffusion coefficient (ADC) values of lesions. Patient and methods: Thirty-six patients with pancreatic lesions (12 malignant and 24 benign) were included. MRI-c and DWI (b values 500 and 1000 s/mm2) were performed prospectively and consecutively in a 1.5-T system. Results: The analysis was retrospectively performed. The sensitivity, specificity, accuracy, and positive and negative predictive values of DWI and MRI-c were 92%, 97%, 96%, 85%, 98% and 100%, 97%, 97%, 86%, 100%, respectively. Mean ADC values of malignant lesions were significantly lower than those of benign lesions. DWI has a similar accuracy to MRI-c in diagnosis of pancreas cancer. Conclusion: Malignant tumors had lower ADC values than benign ones. DWI may be a routine sequence in oncologic settings and it provides much useful information about tumoral tissue.
first_indexed 2024-12-20T08:38:48Z
format Article
id doaj.art-6efda1df5027499cb8c455e7e279d1bd
institution Directory Open Access Journal
issn 0378-603X
language English
last_indexed 2024-12-20T08:38:48Z
publishDate 2015-09-01
publisher SpringerOpen
record_format Article
series The Egyptian Journal of Radiology and Nuclear Medicine
spelling doaj.art-6efda1df5027499cb8c455e7e279d1bd2022-12-21T19:46:27ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2015-09-0146356356810.1016/j.ejrnm.2015.03.009Differentiation of Pancreatic lesions using Diffusion-Weighted MRIMohamad Hamid Abo Warda0Doaa Ibrahim Hasan1Osama Abdelaziz Elteeh2Diagnostic Radiology Department, Zagazig University Hospitals, EgyptDiagnostic Radiology Department, Zagazig University Hospitals, EgyptGeneral Surgery Department, Zagazig University Hospitals, EgyptThe purpose of this study was to evaluate the role of diffusion-weighted imaging (DWI) in diagnosis of pancreatic lesions, to compare diagnostic accuracy of conventional MRI (MRI-c), DWI and diffusion coefficient (ADC) values of lesions. Patient and methods: Thirty-six patients with pancreatic lesions (12 malignant and 24 benign) were included. MRI-c and DWI (b values 500 and 1000 s/mm2) were performed prospectively and consecutively in a 1.5-T system. Results: The analysis was retrospectively performed. The sensitivity, specificity, accuracy, and positive and negative predictive values of DWI and MRI-c were 92%, 97%, 96%, 85%, 98% and 100%, 97%, 97%, 86%, 100%, respectively. Mean ADC values of malignant lesions were significantly lower than those of benign lesions. DWI has a similar accuracy to MRI-c in diagnosis of pancreas cancer. Conclusion: Malignant tumors had lower ADC values than benign ones. DWI may be a routine sequence in oncologic settings and it provides much useful information about tumoral tissue.http://www.sciencedirect.com/science/article/pii/S0378603X15000662PancreasMagnetic resonance imaging (MRI)Diffusion weighted imaging (DWI)Neoplasm
spellingShingle Mohamad Hamid Abo Warda
Doaa Ibrahim Hasan
Osama Abdelaziz Elteeh
Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
The Egyptian Journal of Radiology and Nuclear Medicine
Pancreas
Magnetic resonance imaging (MRI)
Diffusion weighted imaging (DWI)
Neoplasm
title Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
title_full Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
title_fullStr Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
title_full_unstemmed Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
title_short Differentiation of Pancreatic lesions using Diffusion-Weighted MRI
title_sort differentiation of pancreatic lesions using diffusion weighted mri
topic Pancreas
Magnetic resonance imaging (MRI)
Diffusion weighted imaging (DWI)
Neoplasm
url http://www.sciencedirect.com/science/article/pii/S0378603X15000662
work_keys_str_mv AT mohamadhamidabowarda differentiationofpancreaticlesionsusingdiffusionweightedmri
AT doaaibrahimhasan differentiationofpancreaticlesionsusingdiffusionweightedmri
AT osamaabdelazizelteeh differentiationofpancreaticlesionsusingdiffusionweightedmri