Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes
Interest in the synthesis of Bi(III) and Sb(III) dithiocarbamate complexes is on the rise, and this has been attributed to their wide structural diversity and their interesting application as biological agents and in solid state/materials chemistry. The readily available binding sites of the two sul...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/2/305 |
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| author | Jerry O. Adeyemi Damian C. Onwudiwe |
| author_facet | Jerry O. Adeyemi Damian C. Onwudiwe |
| author_sort | Jerry O. Adeyemi |
| collection | DOAJ |
| description | Interest in the synthesis of Bi(III) and Sb(III) dithiocarbamate complexes is on the rise, and this has been attributed to their wide structural diversity and their interesting application as biological agents and in solid state/materials chemistry. The readily available binding sites of the two sulphur atoms within the dithiocarbamate moiety in the complexes confers a wide variety of geometry and interactions that often leads to supramolecular assemblies. Although none of the bismuth or antimony metals are known to play any natural biological function, their dithiocarbamate complexes, however, have proven very useful as antibacterial, antileishmanial, anticancer, and antifungal agents. The dithiocarbamate ligands modulate the associated toxicity of the metals, especially antimony, since bismuth is known to be benign, allowing the metal ion to get to the targeted sites; hence, making it less available for side and other damaging reactions. This review presents a concise chemistry and some known biological potentials of their trivalent dithiocarbamate complexes. |
| first_indexed | 2024-12-12T06:27:47Z |
| format | Article |
| id | doaj.art-6f02d088d7b74646a92b51258e040836 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T06:27:47Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6f02d088d7b74646a92b51258e0408362022-12-22T00:34:42ZengMDPI AGMolecules1420-30492020-01-0125230510.3390/molecules25020305molecules25020305Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate ComplexesJerry O. Adeyemi0Damian C. Onwudiwe1Material Science Innovation and Modelling (MaSIM) Research Focus Area, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South AfricaMaterial Science Innovation and Modelling (MaSIM) Research Focus Area, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South AfricaInterest in the synthesis of Bi(III) and Sb(III) dithiocarbamate complexes is on the rise, and this has been attributed to their wide structural diversity and their interesting application as biological agents and in solid state/materials chemistry. The readily available binding sites of the two sulphur atoms within the dithiocarbamate moiety in the complexes confers a wide variety of geometry and interactions that often leads to supramolecular assemblies. Although none of the bismuth or antimony metals are known to play any natural biological function, their dithiocarbamate complexes, however, have proven very useful as antibacterial, antileishmanial, anticancer, and antifungal agents. The dithiocarbamate ligands modulate the associated toxicity of the metals, especially antimony, since bismuth is known to be benign, allowing the metal ion to get to the targeted sites; hence, making it less available for side and other damaging reactions. This review presents a concise chemistry and some known biological potentials of their trivalent dithiocarbamate complexes.https://www.mdpi.com/1420-3049/25/2/305bismuthantimonydithiocarbamatebiological activitiesstructural properties |
| spellingShingle | Jerry O. Adeyemi Damian C. Onwudiwe Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes Molecules bismuth antimony dithiocarbamate biological activities structural properties |
| title | Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes |
| title_full | Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes |
| title_fullStr | Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes |
| title_full_unstemmed | Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes |
| title_short | Chemistry and Some Biological Potential of Bismuth and Antimony Dithiocarbamate Complexes |
| title_sort | chemistry and some biological potential of bismuth and antimony dithiocarbamate complexes |
| topic | bismuth antimony dithiocarbamate biological activities structural properties |
| url | https://www.mdpi.com/1420-3049/25/2/305 |
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