Single-cell RNA sequencing reveals the Müller subtypes and inner blood–retinal barrier regulatory network in early diabetic retinopathy

Single-cell RNA sequencing reveals the Müller subtypes and inner blood–retinal barrier regulatory network in early diabetic retinopathy

As the basic pathological changes of diabetic retinopathy (DR), the destruction of the blood-retina barrier (BRB) and vascular leakage have attracted extensive attention. Without timely intervention, BRB damage will eventually lead to serious visual impairment. However, due to the delicate structure...

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Bibliographic Details
Main Authors: Yan Wang, Xiongyi Yang, Qiumo Li, Yuxi Zhang, Lin Chen, Libing Hong, Zhuohang Xie, Siyu Yang, Xiaoqing Deng, Mingzhe Cao, Guoguo Yi, Min Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
single-cell RNA sequencing
blood–retinal barrier
Müller cell
diabetic retinopathy
communication network
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1048634/full

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