Aggressive oral granular cell tumor with periorbital involvement: An unusual case

Granular cell tumor (GCT) of the oral cavity is rare and so is the involvement of the eye, orbit, and ocular adnexa. A 65-year-old male developed a posttraumatic ulceroproliferative mass over his left cheek for the past 1 year. The mass involved the periorbital region with accompanying blood-stained...

Full description

Bibliographic Details
Main Authors: Rajiv Garg, Gunjan Rana, Siddharth Madan, Anita Nangia, Rekha Yadav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=6;spage=544;epage=548;aulast=Garg
_version_ 1818929861488541696
author Rajiv Garg
Gunjan Rana
Siddharth Madan
Anita Nangia
Rekha Yadav
author_facet Rajiv Garg
Gunjan Rana
Siddharth Madan
Anita Nangia
Rekha Yadav
author_sort Rajiv Garg
collection DOAJ
description Granular cell tumor (GCT) of the oral cavity is rare and so is the involvement of the eye, orbit, and ocular adnexa. A 65-year-old male developed a posttraumatic ulceroproliferative mass over his left cheek for the past 1 year. The mass involved the periorbital region with accompanying blood-stained purulent discharge from multiple sinus tracts over this lesion for the past 6 months. Radiographs of the orbit suggested chronic osteomyelitis. The lesion was not responsive to treatment with antibiotics. Enlarged submandibular lymph node demonstrated reactive lymphadenitis on cytological examination. However, computed tomography scan of the paranasal sinus (PNS) revealed possibly a malignant mass extending into the maxillary sinus and left extraconal space. Surprisingly, histopathological examination and immunohistochemistry from a growth involving the left upper retromolar region that extended up to the midline and periorbital region suggested a diagnosis of GCT. This unusual and new presentation of GCT is not well known to the dentists and also to the ophthalmologists. It is imperative to examine anatomically neighboring structures, especially the eye, nasal cavity, PNSs, and oval cavity among other structures in an underlying pathology in either of these sites.
first_indexed 2024-12-20T03:51:32Z
format Article
id doaj.art-6f10ccc343314412b261c01185125a0a
institution Directory Open Access Journal
issn 0972-124X
language English
last_indexed 2024-12-20T03:51:32Z
publishDate 2021-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Indian Society of Periodontology
spelling doaj.art-6f10ccc343314412b261c01185125a0a2022-12-21T19:54:27ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2021-01-0125654454810.4103/jisp.jisp_435_20Aggressive oral granular cell tumor with periorbital involvement: An unusual caseRajiv GargGunjan RanaSiddharth MadanAnita NangiaRekha YadavGranular cell tumor (GCT) of the oral cavity is rare and so is the involvement of the eye, orbit, and ocular adnexa. A 65-year-old male developed a posttraumatic ulceroproliferative mass over his left cheek for the past 1 year. The mass involved the periorbital region with accompanying blood-stained purulent discharge from multiple sinus tracts over this lesion for the past 6 months. Radiographs of the orbit suggested chronic osteomyelitis. The lesion was not responsive to treatment with antibiotics. Enlarged submandibular lymph node demonstrated reactive lymphadenitis on cytological examination. However, computed tomography scan of the paranasal sinus (PNS) revealed possibly a malignant mass extending into the maxillary sinus and left extraconal space. Surprisingly, histopathological examination and immunohistochemistry from a growth involving the left upper retromolar region that extended up to the midline and periorbital region suggested a diagnosis of GCT. This unusual and new presentation of GCT is not well known to the dentists and also to the ophthalmologists. It is imperative to examine anatomically neighboring structures, especially the eye, nasal cavity, PNSs, and oval cavity among other structures in an underlying pathology in either of these sites.http://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=6;spage=544;epage=548;aulast=Garggranular cell tumorimmunohistochemistryoral cavityperiorbital tumorsretromolar granular cell tumor
spellingShingle Rajiv Garg
Gunjan Rana
Siddharth Madan
Anita Nangia
Rekha Yadav
Aggressive oral granular cell tumor with periorbital involvement: An unusual case
Journal of Indian Society of Periodontology
granular cell tumor
immunohistochemistry
oral cavity
periorbital tumors
retromolar granular cell tumor
title Aggressive oral granular cell tumor with periorbital involvement: An unusual case
title_full Aggressive oral granular cell tumor with periorbital involvement: An unusual case
title_fullStr Aggressive oral granular cell tumor with periorbital involvement: An unusual case
title_full_unstemmed Aggressive oral granular cell tumor with periorbital involvement: An unusual case
title_short Aggressive oral granular cell tumor with periorbital involvement: An unusual case
title_sort aggressive oral granular cell tumor with periorbital involvement an unusual case
topic granular cell tumor
immunohistochemistry
oral cavity
periorbital tumors
retromolar granular cell tumor
url http://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=6;spage=544;epage=548;aulast=Garg
work_keys_str_mv AT rajivgarg aggressiveoralgranularcelltumorwithperiorbitalinvolvementanunusualcase
AT gunjanrana aggressiveoralgranularcelltumorwithperiorbitalinvolvementanunusualcase
AT siddharthmadan aggressiveoralgranularcelltumorwithperiorbitalinvolvementanunusualcase
AT anitanangia aggressiveoralgranularcelltumorwithperiorbitalinvolvementanunusualcase
AT rekhayadav aggressiveoralgranularcelltumorwithperiorbitalinvolvementanunusualcase