Protocol for a randomized clinical trial exploring the effect of antimicrobial agents on the penile microbiota, immunology and HIV susceptibility of Ugandan men

Protocol for a randomized clinical trial exploring the effect of antimicrobial agents on the penile microbiota, immunology and HIV susceptibility of Ugandan men

Abstract Background The foreskin is the main site of HIV acquisition in a heterosexual uncircumcised man, but many men in endemic countries are reluctant to undergo penile circumcision (PC). Observational studies suggest that proinflammatory anaerobic bacteria are enriched on the uncircumcised penis...

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Bibliographic Details
Main Authors: Ronald M. Galiwango, Bernard Bagaya, Juliet Mpendo, Vineet Joag, Brenda Okech, Annet Nanvubya, Ali Ssetaala, Moses Muwanga, Rupert Kaul
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Trials
Subjects:
HIV transmission
Penile microbiome
Clinical trial
Antimicrobials
Uganda
Online Access:http://link.springer.com/article/10.1186/s13063-019-3545-7

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