Long-COVID, neurological and cardiovascular disorders

Introduction. After the disease COVID-19 caused by the SARS-CoV-2 virus, many people recover completely, but others have symptoms that persist for weeks, months or even years after the illness, with the number of patients who are worried about the signs of Long-COVID constantly growing. The aim....

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Main Authors: Oleksandr Saienko, Mykola Chemych, Vladyslav Svitailo
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-03-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/43431
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author Oleksandr Saienko
Mykola Chemych
Vladyslav Svitailo
author_facet Oleksandr Saienko
Mykola Chemych
Vladyslav Svitailo
author_sort Oleksandr Saienko
collection DOAJ
description Introduction. After the disease COVID-19 caused by the SARS-CoV-2 virus, many people recover completely, but others have symptoms that persist for weeks, months or even years after the illness, with the number of patients who are worried about the signs of Long-COVID constantly growing. The aim. Study of the features of the epidemiological and clinical course, pathophysiological mechanisms of long-COVID development, based on the study and analysis  of modern scientific data and the establishment of causal relationships of damage to the nervous and cardiovascular systems.   Materials and methods. The electronic databases Scopus, PubMed, Web of Science, using modern technologies (Obsidian), key terms and words related to Long COVID, distant neurological and cardio-vascular complications have been studied and analyzed. Conclusions. "Long COVID" is conceptualized as a multiorgan disorder with a wide range of clinical signs that may indicate primarily damage to the nervous and cardiovascular systems. Central or peripheral nervous system lesions occur in more than one-third of patients. Cardiovascular complications, including stroke, are the predominant causes of death of people with "long COVID" (40 %). The most frequent neurological signs of "Long COVID" (>70 %) are fatigue, headache, sleep disorders, emotional disorders and sensorimotor disorders. The processes of neuroinflammatory and oxidative stress predominate in the spread of neurological consequences of "Long COVID".
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spelling doaj.art-6f1aee56baed4b7f8256003dba950b9c2023-04-15T10:45:24ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-03-0113310.12775/JEHS.2023.13.03.048Long-COVID, neurological and cardiovascular disordersOleksandr Saienko0Mykola Chemych1Vladyslav Svitailo2Sumy State UniversitySumy State UniversitySumy State University Introduction. After the disease COVID-19 caused by the SARS-CoV-2 virus, many people recover completely, but others have symptoms that persist for weeks, months or even years after the illness, with the number of patients who are worried about the signs of Long-COVID constantly growing. The aim. Study of the features of the epidemiological and clinical course, pathophysiological mechanisms of long-COVID development, based on the study and analysis  of modern scientific data and the establishment of causal relationships of damage to the nervous and cardiovascular systems.   Materials and methods. The electronic databases Scopus, PubMed, Web of Science, using modern technologies (Obsidian), key terms and words related to Long COVID, distant neurological and cardio-vascular complications have been studied and analyzed. Conclusions. "Long COVID" is conceptualized as a multiorgan disorder with a wide range of clinical signs that may indicate primarily damage to the nervous and cardiovascular systems. Central or peripheral nervous system lesions occur in more than one-third of patients. Cardiovascular complications, including stroke, are the predominant causes of death of people with "long COVID" (40 %). The most frequent neurological signs of "Long COVID" (>70 %) are fatigue, headache, sleep disorders, emotional disorders and sensorimotor disorders. The processes of neuroinflammatory and oxidative stress predominate in the spread of neurological consequences of "Long COVID". https://apcz.umk.pl/JEHS/article/view/43431COVID-19Long-COVIDclinical signsnervous and cardiovascular systemscognitive impairmentconsequences
spellingShingle Oleksandr Saienko
Mykola Chemych
Vladyslav Svitailo
Long-COVID, neurological and cardiovascular disorders
Journal of Education, Health and Sport
COVID-19
Long-COVID
clinical signs
nervous and cardiovascular systems
cognitive impairment
consequences
title Long-COVID, neurological and cardiovascular disorders
title_full Long-COVID, neurological and cardiovascular disorders
title_fullStr Long-COVID, neurological and cardiovascular disorders
title_full_unstemmed Long-COVID, neurological and cardiovascular disorders
title_short Long-COVID, neurological and cardiovascular disorders
title_sort long covid neurological and cardiovascular disorders
topic COVID-19
Long-COVID
clinical signs
nervous and cardiovascular systems
cognitive impairment
consequences
url https://apcz.umk.pl/JEHS/article/view/43431
work_keys_str_mv AT oleksandrsaienko longcovidneurologicalandcardiovasculardisorders
AT mykolachemych longcovidneurologicalandcardiovasculardisorders
AT vladyslavsvitailo longcovidneurologicalandcardiovasculardisorders