Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

Aims: Hyperglucagonaemia contributes to the pathophysiology in type 2 diabetes (T2D), but the mechanisms behind the inappropriate glucagon secretion are not fully understood. Glucagon and amino acids are regulated in a feedback loop referred to as the liver–α cell axis. Individuals with non-alcoholi...

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Bibliographic Details
Main Authors: Iben Rix, Marie L Johansen, Asger Lund, Malte P Suppli, Elizaveta Chabanova, Gerrit van Hall, Jens J Holst, Nicolai J Wewer Albrechtsen, Caroline Kistorp, Filip K Knop
Format: Article
Language:English
Published: Bioscientifica 2023-12-01
Series:Endocrine Connections
Subjects:
glucagon
amino acids
type 2 diabetes mellitus
non-alcoholic fatty liver disease
humans
Online Access:https://ec.bioscientifica.com/view/journals/ec/13/1/EC-23-0161.xml

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