Gene editing therapy ready for cardiovascular diseases: opportunities, challenges, and perspectives

Gene editing nucleases (GENs), represented by CRISPR/Cas9, have become major tools in biomedical research and offer potential cures for many human diseases. Gene editing therapy (GETx) studies in animal models targeting genes such as proprotein convertase subtilisin/kexin type 9 (PCSK9), apolipoprot...

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Bibliographic Details
Main Authors: Zhou Jun, Ren Zhuoying, Xu Jie, Zhang Jifeng, Chen Y. Eugene
Format: Article
Language:English
Published: De Gruyter 2021-10-01
Series:Medical Review
Subjects:
Online Access:https://doi.org/10.1515/mr-2021-0010

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