Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data

Medicines are essential for the treatment of acute, communicable, and non-communicable diseases. The World Health Organization developed a toolkit for drug (medicine) utilization studies to assist in reviewing and evaluating the prescribing, dispensing, and use of medicines. There is a growing need...

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Main Authors: Samantha Hollingworth, Therése Kairuz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmacy
Subjects:
Online Access:https://www.mdpi.com/2226-4787/9/1/60
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author Samantha Hollingworth
Therése Kairuz
author_facet Samantha Hollingworth
Therése Kairuz
author_sort Samantha Hollingworth
collection DOAJ
description Medicines are essential for the treatment of acute, communicable, and non-communicable diseases. The World Health Organization developed a toolkit for drug (medicine) utilization studies to assist in reviewing and evaluating the prescribing, dispensing, and use of medicines. There is a growing need for rigorous studies of medicine use in low- and middle-income countries (LMIC) using standard approaches, especially in the context of universal health coverage. This commentary provides a succinct summary of how to use the WHO anatomical therapeutic chemical (ATC)/defined daily dose (DDD) methodology in pharmacoepidemiological studies, with a focus on LMIC contexts. We drew on information from WHO resources and published literature, citing examples and case studies. We encourage readers to publish their drug utilization studies, although we caution about predatory journals. We recommend the use of the RECORD-PE initiative which focuses on methods for doing pharmacoepidemiological research and evaluating the quality of published papers.
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spelling doaj.art-6f23d0e3b44d46f39bbfbbdcd7d82f882023-11-21T10:50:04ZengMDPI AGPharmacy2226-47872021-03-01916010.3390/pharmacy9010060Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World DataSamantha Hollingworth0Therése Kairuz1School of Pharmacy, University of Queensland, Woolloongabba, QLD 4102, AustraliaSchool of Pharmacy, University of Newcastle, Callaghan, NSW 2308, AustraliaMedicines are essential for the treatment of acute, communicable, and non-communicable diseases. The World Health Organization developed a toolkit for drug (medicine) utilization studies to assist in reviewing and evaluating the prescribing, dispensing, and use of medicines. There is a growing need for rigorous studies of medicine use in low- and middle-income countries (LMIC) using standard approaches, especially in the context of universal health coverage. This commentary provides a succinct summary of how to use the WHO anatomical therapeutic chemical (ATC)/defined daily dose (DDD) methodology in pharmacoepidemiological studies, with a focus on LMIC contexts. We drew on information from WHO resources and published literature, citing examples and case studies. We encourage readers to publish their drug utilization studies, although we caution about predatory journals. We recommend the use of the RECORD-PE initiative which focuses on methods for doing pharmacoepidemiological research and evaluating the quality of published papers.https://www.mdpi.com/2226-4787/9/1/60medicinespharmacoepidemiologyATCDDDdrug utilization
spellingShingle Samantha Hollingworth
Therése Kairuz
Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
Pharmacy
medicines
pharmacoepidemiology
ATC
DDD
drug utilization
title Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
title_full Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
title_fullStr Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
title_full_unstemmed Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
title_short Measuring Medicine Use: Applying ATC/DDD Methodology to Real-World Data
title_sort measuring medicine use applying atc ddd methodology to real world data
topic medicines
pharmacoepidemiology
ATC
DDD
drug utilization
url https://www.mdpi.com/2226-4787/9/1/60
work_keys_str_mv AT samanthahollingworth measuringmedicineuseapplyingatcdddmethodologytorealworlddata
AT theresekairuz measuringmedicineuseapplyingatcdddmethodologytorealworlddata