Mendelian randomization indicates causal effects of estradiol levels on kidney function in males

Mendelian randomization indicates causal effects of estradiol levels on kidney function in males

ContextChronic kidney disease (CKD) is a public health burden worldwide. Epidemiological studies observed an association between sex hormones, including estradiol, and kidney function.ObjectiveWe conducted a Mendelian randomization (MR) study to assess a possible causal effect of estradiol levels on...

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Bibliographic Details
Main Authors: M. Kamal Nasr, Claudia Schurmann, Erwin P. Böttinger, Alexander Teumer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
glomerular filtration rate
steroids
albuminuria
genome-wide association study
causality
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1232266/full

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