Gene Expression Profiling of Classically Activated Macrophages in <i>Leishmania infantum</i> Infection: Response to Metabolic Pre-Stimulus with Itaconic Acid

Gene Expression Profiling of Classically Activated Macrophages in <i>Leishmania infantum</i> Infection: Response to Metabolic Pre-Stimulus with Itaconic Acid

<i>Leishmania</i> infection of phagocytic cells, such as macrophages, induces the differentiation of infected cells into different phenotypes according to their surrounding microenvironments. The classical activation of macrophages involves metabolic reprogramming, in which several metab...

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Bibliographic Details
Main Authors: Génesis Palacios, Elva Vega-García, Basilio Valladares, José Antonio Pérez, Roberto Dorta-Guerra, Emma Carmelo
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Tropical Medicine and Infectious Disease
Subjects:
gene expression profiling
macrophage activation
classically activated macrophages
metabolic stimulus
itaconate
<i>Leishmania infantum</i>
Online Access:https://www.mdpi.com/2414-6366/8/5/264

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