Personalized nutrition: A review of genotype-based nutritional supplementation
Nutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genom...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Nutrition |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/full |
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author | Feijie Wang Jianheng Zheng Junrui Cheng Hong Zou Mingfeng Li Bin Deng Rong Luo Feng Wang Dingqiang Huang Gang Li Rao Zhang Xin Ding Yuan Li Jun Du Yuexin Yang Juntao Kan |
author_facet | Feijie Wang Jianheng Zheng Junrui Cheng Hong Zou Mingfeng Li Bin Deng Rong Luo Feng Wang Dingqiang Huang Gang Li Rao Zhang Xin Ding Yuan Li Jun Du Yuexin Yang Juntao Kan |
author_sort | Feijie Wang |
collection | DOAJ |
description | Nutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genomics and nutrigenetics, accumulation of genetic variants has been indicated to alter the effects of nutritional supplementation, suggesting its indispensable role in the genotype-based personalized nutrition. Additionally, the metabolism of nutrients, such as lipids, especially omega-3 polyunsaturated fatty acids, glucose, vitamin A, folic acid, vitamin D, iron, and calcium could be effectively improved with related genetic variants. This review focuses on existing literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations. Although further studies are required in this direction, such evidence provides valuable insights for the guidance of appropriate interventions using genetic information, thus paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition. |
first_indexed | 2024-04-12T04:52:30Z |
format | Article |
id | doaj.art-6f26e304b04941d4a074c5a24ffd38c6 |
institution | Directory Open Access Journal |
issn | 2296-861X |
language | English |
last_indexed | 2024-04-12T04:52:30Z |
publishDate | 2022-09-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Nutrition |
spelling | doaj.art-6f26e304b04941d4a074c5a24ffd38c62022-12-22T03:47:15ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-09-01910.3389/fnut.2022.992986992986Personalized nutrition: A review of genotype-based nutritional supplementationFeijie Wang0Jianheng Zheng1Junrui Cheng2Hong Zou3Mingfeng Li4Bin Deng5Rong Luo6Feng Wang7Dingqiang Huang8Gang Li9Rao Zhang10Xin Ding11Yuan Li12Jun Du13Yuexin Yang14Juntao Kan15Nutrilite Health Institute, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaDepartment of Molecular and Structural Biochemistry, North Carolina State University, Kannapolis, NC, United StatesSequanta Technologies Co., Ltd, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Shanghai, ChinaSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, ChinaSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, ChinaSequanta Technologies Co., Ltd, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaChinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Beijing, ChinaNutrilite Health Institute, Shanghai, ChinaNutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genomics and nutrigenetics, accumulation of genetic variants has been indicated to alter the effects of nutritional supplementation, suggesting its indispensable role in the genotype-based personalized nutrition. Additionally, the metabolism of nutrients, such as lipids, especially omega-3 polyunsaturated fatty acids, glucose, vitamin A, folic acid, vitamin D, iron, and calcium could be effectively improved with related genetic variants. This review focuses on existing literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations. Although further studies are required in this direction, such evidence provides valuable insights for the guidance of appropriate interventions using genetic information, thus paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition.https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/fullpersonalized nutritionnutritional supplementationnutrientgenotypesingle nucleotide polymorphismsnutrigenetics |
spellingShingle | Feijie Wang Jianheng Zheng Junrui Cheng Hong Zou Mingfeng Li Bin Deng Rong Luo Feng Wang Dingqiang Huang Gang Li Rao Zhang Xin Ding Yuan Li Jun Du Yuexin Yang Juntao Kan Personalized nutrition: A review of genotype-based nutritional supplementation Frontiers in Nutrition personalized nutrition nutritional supplementation nutrient genotype single nucleotide polymorphisms nutrigenetics |
title | Personalized nutrition: A review of genotype-based nutritional supplementation |
title_full | Personalized nutrition: A review of genotype-based nutritional supplementation |
title_fullStr | Personalized nutrition: A review of genotype-based nutritional supplementation |
title_full_unstemmed | Personalized nutrition: A review of genotype-based nutritional supplementation |
title_short | Personalized nutrition: A review of genotype-based nutritional supplementation |
title_sort | personalized nutrition a review of genotype based nutritional supplementation |
topic | personalized nutrition nutritional supplementation nutrient genotype single nucleotide polymorphisms nutrigenetics |
url | https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/full |
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