Personalized nutrition: A review of genotype-based nutritional supplementation

Nutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genom...

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Main Authors: Feijie Wang, Jianheng Zheng, Junrui Cheng, Hong Zou, Mingfeng Li, Bin Deng, Rong Luo, Feng Wang, Dingqiang Huang, Gang Li, Rao Zhang, Xin Ding, Yuan Li, Jun Du, Yuexin Yang, Juntao Kan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/full
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author Feijie Wang
Jianheng Zheng
Junrui Cheng
Hong Zou
Mingfeng Li
Bin Deng
Rong Luo
Feng Wang
Dingqiang Huang
Gang Li
Rao Zhang
Xin Ding
Yuan Li
Jun Du
Yuexin Yang
Juntao Kan
author_facet Feijie Wang
Jianheng Zheng
Junrui Cheng
Hong Zou
Mingfeng Li
Bin Deng
Rong Luo
Feng Wang
Dingqiang Huang
Gang Li
Rao Zhang
Xin Ding
Yuan Li
Jun Du
Yuexin Yang
Juntao Kan
author_sort Feijie Wang
collection DOAJ
description Nutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genomics and nutrigenetics, accumulation of genetic variants has been indicated to alter the effects of nutritional supplementation, suggesting its indispensable role in the genotype-based personalized nutrition. Additionally, the metabolism of nutrients, such as lipids, especially omega-3 polyunsaturated fatty acids, glucose, vitamin A, folic acid, vitamin D, iron, and calcium could be effectively improved with related genetic variants. This review focuses on existing literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations. Although further studies are required in this direction, such evidence provides valuable insights for the guidance of appropriate interventions using genetic information, thus paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition.
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spelling doaj.art-6f26e304b04941d4a074c5a24ffd38c62022-12-22T03:47:15ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-09-01910.3389/fnut.2022.992986992986Personalized nutrition: A review of genotype-based nutritional supplementationFeijie Wang0Jianheng Zheng1Junrui Cheng2Hong Zou3Mingfeng Li4Bin Deng5Rong Luo6Feng Wang7Dingqiang Huang8Gang Li9Rao Zhang10Xin Ding11Yuan Li12Jun Du13Yuexin Yang14Juntao Kan15Nutrilite Health Institute, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaDepartment of Molecular and Structural Biochemistry, North Carolina State University, Kannapolis, NC, United StatesSequanta Technologies Co., Ltd, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Guangzhou, ChinaNutrilite Health Institute, Shanghai, ChinaSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, ChinaSchool of Public Health, Institute of Nutrition and Health, Qingdao University, Qingdao, ChinaSequanta Technologies Co., Ltd, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaChinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Beijing, ChinaNutrilite Health Institute, Shanghai, ChinaNutritional disorders have become a major public health issue, requiring increased targeted approaches. Personalized nutrition adapted to individual needs has garnered dramatic attention as an effective way to improve nutritional balance and maintain health. With the rapidly evolving fields of genomics and nutrigenetics, accumulation of genetic variants has been indicated to alter the effects of nutritional supplementation, suggesting its indispensable role in the genotype-based personalized nutrition. Additionally, the metabolism of nutrients, such as lipids, especially omega-3 polyunsaturated fatty acids, glucose, vitamin A, folic acid, vitamin D, iron, and calcium could be effectively improved with related genetic variants. This review focuses on existing literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations. Although further studies are required in this direction, such evidence provides valuable insights for the guidance of appropriate interventions using genetic information, thus paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition.https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/fullpersonalized nutritionnutritional supplementationnutrientgenotypesingle nucleotide polymorphismsnutrigenetics
spellingShingle Feijie Wang
Jianheng Zheng
Junrui Cheng
Hong Zou
Mingfeng Li
Bin Deng
Rong Luo
Feng Wang
Dingqiang Huang
Gang Li
Rao Zhang
Xin Ding
Yuan Li
Jun Du
Yuexin Yang
Juntao Kan
Personalized nutrition: A review of genotype-based nutritional supplementation
Frontiers in Nutrition
personalized nutrition
nutritional supplementation
nutrient
genotype
single nucleotide polymorphisms
nutrigenetics
title Personalized nutrition: A review of genotype-based nutritional supplementation
title_full Personalized nutrition: A review of genotype-based nutritional supplementation
title_fullStr Personalized nutrition: A review of genotype-based nutritional supplementation
title_full_unstemmed Personalized nutrition: A review of genotype-based nutritional supplementation
title_short Personalized nutrition: A review of genotype-based nutritional supplementation
title_sort personalized nutrition a review of genotype based nutritional supplementation
topic personalized nutrition
nutritional supplementation
nutrient
genotype
single nucleotide polymorphisms
nutrigenetics
url https://www.frontiersin.org/articles/10.3389/fnut.2022.992986/full
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