Oncocytoma-Related Gene Signature to Differentiate Chromophobe Renal Cancer and Oncocytoma Using Machine Learning

Oncocytoma-Related Gene Signature to Differentiate Chromophobe Renal Cancer and Oncocytoma Using Machine Learning

Publicly available gene expression datasets were analyzed to develop a chromophobe and oncocytoma related gene signature (COGS) to distinguish chRCC from RO. The datasets GSE11151, GSE19982, GSE2109, GSE8271 and GSE11024 were combined into a discovery dataset. The transcriptomic differences were ide...

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Bibliographic Details
Main Authors: Khaled Bin Satter, Paul Minh Huy Tran, Lynn Kim Hoang Tran, Zach Ramsey, Katheine Pinkerton, Shan Bai, Natasha M. Savage, Sravan Kavuri, Martha K. Terris, Jin-Xiong She, Sharad Purohit
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
chromophobe
oncocytoma
classification
machine learning
transcriptomic
gene signature
Online Access:https://www.mdpi.com/2073-4409/11/2/287

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