Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy
On the basis of an article previously published in the journal regarding immune persistence after hepatitis B vaccination in infancy, I discuss why this persistence is a fact and not a fancy. Immune memory after a primary vaccination series has been widely demonstrated by prompt response to booster...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2017-04-01
|
| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2016.1257451 |
| _version_ | 1797674551270703104 |
|---|---|
| author | Andrea Trevisan |
| author_facet | Andrea Trevisan |
| author_sort | Andrea Trevisan |
| collection | DOAJ |
| description | On the basis of an article previously published in the journal regarding immune persistence after hepatitis B vaccination in infancy, I discuss why this persistence is a fact and not a fancy. Immune memory after a primary vaccination series has been widely demonstrated by prompt response to booster doses and the proliferation of T cells secreting IFNγ. In a large cohort of medical students, 79% of subjects were positive for anti-HBs antibodies, and only 1.9% of the subjects had serological evidence of past hepatitis B infection. To prevent severe diseases, such as hepatitis B, it is very important that the majority of the population is vaccinated, especially those employed in health care, as vaccination is the most effective weapon to hepatitis B, which is still widespread worldwide. |
| first_indexed | 2024-03-11T22:01:43Z |
| format | Article |
| id | doaj.art-6f2ecf656f604c9a972960a888a7a658 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:01:43Z |
| publishDate | 2017-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-6f2ecf656f604c9a972960a888a7a6582023-09-25T11:00:55ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2017-04-0113491691710.1080/21645515.2016.12574511257451Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancyAndrea Trevisan0Thoracic and Vascular Sciences, Unit of Preventive Medicine and Risk Assessment, University of PadovaOn the basis of an article previously published in the journal regarding immune persistence after hepatitis B vaccination in infancy, I discuss why this persistence is a fact and not a fancy. Immune memory after a primary vaccination series has been widely demonstrated by prompt response to booster doses and the proliferation of T cells secreting IFNγ. In a large cohort of medical students, 79% of subjects were positive for anti-HBs antibodies, and only 1.9% of the subjects had serological evidence of past hepatitis B infection. To prevent severe diseases, such as hepatitis B, it is very important that the majority of the population is vaccinated, especially those employed in health care, as vaccination is the most effective weapon to hepatitis B, which is still widespread worldwide.http://dx.doi.org/10.1080/21645515.2016.1257451antibody persistencehepatitis b vaccinehepatitis b virusimmune coverage |
| spellingShingle | Andrea Trevisan Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy Human Vaccines & Immunotherapeutics antibody persistence hepatitis b vaccine hepatitis b virus immune coverage |
| title | Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy |
| title_full | Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy |
| title_fullStr | Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy |
| title_full_unstemmed | Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy |
| title_short | Long-term persistence of immunity after hepatitis B vaccination: A fact, not a fancy |
| title_sort | long term persistence of immunity after hepatitis b vaccination a fact not a fancy |
| topic | antibody persistence hepatitis b vaccine hepatitis b virus immune coverage |
| url | http://dx.doi.org/10.1080/21645515.2016.1257451 |
| work_keys_str_mv | AT andreatrevisan longtermpersistenceofimmunityafterhepatitisbvaccinationafactnotafancy |