Films for Wound Healing Fabricated Using a Solvent Casting Technique
Wound healing is a complex process that involves restoring the structure of damaged tissues through four phases: hemostasis, inflammation, proliferation, and remodeling. Wound dressings are the most common treatment used to cover wounds, reduce infection risk and the loss of physiological fluids, an...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/15/7/1914 |
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| author | Fabiola V. Borbolla-Jiménez Sheila I. Peña-Corona Sonia J. Farah María Teresa Jiménez-Valdés Emiliano Pineda-Pérez Alejandra Romero-Montero María Luisa Del Prado-Audelo Sergio Alberto Bernal-Chávez Jonathan J. Magaña Gerardo Leyva-Gómez |
| author_facet | Fabiola V. Borbolla-Jiménez Sheila I. Peña-Corona Sonia J. Farah María Teresa Jiménez-Valdés Emiliano Pineda-Pérez Alejandra Romero-Montero María Luisa Del Prado-Audelo Sergio Alberto Bernal-Chávez Jonathan J. Magaña Gerardo Leyva-Gómez |
| author_sort | Fabiola V. Borbolla-Jiménez |
| collection | DOAJ |
| description | Wound healing is a complex process that involves restoring the structure of damaged tissues through four phases: hemostasis, inflammation, proliferation, and remodeling. Wound dressings are the most common treatment used to cover wounds, reduce infection risk and the loss of physiological fluids, and enhance wound healing. Despite there being several types of wound dressings based on different materials and fabricated through various techniques, polymeric films have been widely employed due to their biocompatibility and low immunogenicity. Furthermore, they are non-invasive, easy to apply, allow gas exchange, and can be transparent. Among different methods for designing polymeric films, solvent casting represents a reliable, preferable, and highly used technique due to its easygoing and relatively low-cost procedure compared to sophisticated methods such as spin coating, microfluidic spinning, or 3D printing. Therefore, this review focuses on the polymeric dressings obtained using this technique, emphasizing the critical manufacturing factors related to pharmaceuticals, specifically discussing the formulation variables necessary to create wound dressings that demonstrate effective performance. |
| first_indexed | 2024-03-11T00:44:00Z |
| format | Article |
| id | doaj.art-6f30337c31564ff3b11e79a6f2f6c212 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-11T00:44:00Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-6f30337c31564ff3b11e79a6f2f6c2122023-11-18T20:55:36ZengMDPI AGPharmaceutics1999-49232023-07-01157191410.3390/pharmaceutics15071914Films for Wound Healing Fabricated Using a Solvent Casting TechniqueFabiola V. Borbolla-Jiménez0Sheila I. Peña-Corona1Sonia J. Farah2María Teresa Jiménez-Valdés3Emiliano Pineda-Pérez4Alejandra Romero-Montero5María Luisa Del Prado-Audelo6Sergio Alberto Bernal-Chávez7Jonathan J. Magaña8Gerardo Leyva-Gómez9Laboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, MexicoDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, MexicoLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, MexicoLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, MexicoLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, MexicoDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, MexicoTecnologico de Monterrey, Campus Ciudad de México, Ciudad de México 14380, MexicoDepartamento de Ciencias Químico-Biológicas, Universidad de las Américas Puebla, Ex-Hda. de Sta. Catarina Mártir, Cholula 72820, Puebla, MexicoLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México 14389, MexicoDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, MexicoWound healing is a complex process that involves restoring the structure of damaged tissues through four phases: hemostasis, inflammation, proliferation, and remodeling. Wound dressings are the most common treatment used to cover wounds, reduce infection risk and the loss of physiological fluids, and enhance wound healing. Despite there being several types of wound dressings based on different materials and fabricated through various techniques, polymeric films have been widely employed due to their biocompatibility and low immunogenicity. Furthermore, they are non-invasive, easy to apply, allow gas exchange, and can be transparent. Among different methods for designing polymeric films, solvent casting represents a reliable, preferable, and highly used technique due to its easygoing and relatively low-cost procedure compared to sophisticated methods such as spin coating, microfluidic spinning, or 3D printing. Therefore, this review focuses on the polymeric dressings obtained using this technique, emphasizing the critical manufacturing factors related to pharmaceuticals, specifically discussing the formulation variables necessary to create wound dressings that demonstrate effective performance.https://www.mdpi.com/1999-4923/15/7/1914skinwoundwound healingwound dressingspolymersfilms |
| spellingShingle | Fabiola V. Borbolla-Jiménez Sheila I. Peña-Corona Sonia J. Farah María Teresa Jiménez-Valdés Emiliano Pineda-Pérez Alejandra Romero-Montero María Luisa Del Prado-Audelo Sergio Alberto Bernal-Chávez Jonathan J. Magaña Gerardo Leyva-Gómez Films for Wound Healing Fabricated Using a Solvent Casting Technique Pharmaceutics skin wound wound healing wound dressings polymers films |
| title | Films for Wound Healing Fabricated Using a Solvent Casting Technique |
| title_full | Films for Wound Healing Fabricated Using a Solvent Casting Technique |
| title_fullStr | Films for Wound Healing Fabricated Using a Solvent Casting Technique |
| title_full_unstemmed | Films for Wound Healing Fabricated Using a Solvent Casting Technique |
| title_short | Films for Wound Healing Fabricated Using a Solvent Casting Technique |
| title_sort | films for wound healing fabricated using a solvent casting technique |
| topic | skin wound wound healing wound dressings polymers films |
| url | https://www.mdpi.com/1999-4923/15/7/1914 |
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