Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters
Abstract This study examined the physiological effects of replacing some of the casein with either a plant based, animal or combination of protein sources in a high-fat diet fed to golden Syrian hamsters. Cooked kidney beans (BN) and beef (Bf) patties drained of fat were fed at 25 and 50% of diet. A...
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Food Production, Processing and Nutrition |
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| Online Access: | https://doi.org/10.1186/s43014-023-00135-2 |
| _version_ | 1827933257989095424 |
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| author | John W. Finley Darryl Holliday Hyunsook Kim Priscila Leal da Silva Alves Dong-Yan Shao Glenn Bartley Wallace Yokoyama |
| author_facet | John W. Finley Darryl Holliday Hyunsook Kim Priscila Leal da Silva Alves Dong-Yan Shao Glenn Bartley Wallace Yokoyama |
| author_sort | John W. Finley |
| collection | DOAJ |
| description | Abstract This study examined the physiological effects of replacing some of the casein with either a plant based, animal or combination of protein sources in a high-fat diet fed to golden Syrian hamsters. Cooked kidney beans (BN) and beef (Bf) patties drained of fat were fed at 25 and 50% of diet. A combination of BN and Bf (BNBf) was also fed at 25 and 50%. Saturated fat content of the 25% Bf (Bf25) and 50% Bf (Bf50) increased 57 and 215% compared to Control. The Bf diets also increased caloric density compared to the Control. Likewise, the 50% Bn (Bn50) diet had 60% less saturated fat and lower caloric density than the Control. Despite these differences there were no differences in body weight gain or adipose weight between BN of Bf diets and Control. The BN50 diet reduced liver weight and increased caloric intake. The BN diets reduced total plasma cholesterol (TC). The BF diets also reduced TC but the results were not significant. The BN25, BN50 and BNBF50 diets also reduced low density lipoprotein (LDL) cholesterol. The BN and BF50 diets reduced liver fat. The BN diets decreased fecal fat excretion while the BF diets increased excretion. This suggests that increased fat excretion might offset the higher total fat and saturated fat of the BF diets to reduce adverse effects on body weight, adipose weight, and cholesterol. The high-fat content of the base (Control) diet may have muted the effects of the diet treatments. Graphical Abstract |
| first_indexed | 2024-03-13T07:22:17Z |
| format | Article |
| id | doaj.art-6f31c12b4f6043028dba56cc9689646e |
| institution | Directory Open Access Journal |
| issn | 2661-8974 |
| language | English |
| last_indexed | 2024-03-13T07:22:17Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Food Production, Processing and Nutrition |
| spelling | doaj.art-6f31c12b4f6043028dba56cc9689646e2023-06-04T11:34:42ZengBMCFood Production, Processing and Nutrition2661-89742023-06-015111010.1186/s43014-023-00135-2Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamstersJohn W. Finley0Darryl Holliday1Hyunsook Kim2Priscila Leal da Silva Alves3Dong-Yan Shao4Glenn Bartley5Wallace Yokoyama6Department of Food Science, Louisiana State UniversityDepartment of Food Science, Louisiana State UniversityDepartment of Nutrition, University of CaliforniaUSDA, ARS, Western Regional Research Center, HPFRNorthwestern Polytechnical UniversityUSDA, ARS, Western Regional Research Center, HPFRUSDA, ARS, Western Regional Research Center, HPFRAbstract This study examined the physiological effects of replacing some of the casein with either a plant based, animal or combination of protein sources in a high-fat diet fed to golden Syrian hamsters. Cooked kidney beans (BN) and beef (Bf) patties drained of fat were fed at 25 and 50% of diet. A combination of BN and Bf (BNBf) was also fed at 25 and 50%. Saturated fat content of the 25% Bf (Bf25) and 50% Bf (Bf50) increased 57 and 215% compared to Control. The Bf diets also increased caloric density compared to the Control. Likewise, the 50% Bn (Bn50) diet had 60% less saturated fat and lower caloric density than the Control. Despite these differences there were no differences in body weight gain or adipose weight between BN of Bf diets and Control. The BN50 diet reduced liver weight and increased caloric intake. The BN diets reduced total plasma cholesterol (TC). The BF diets also reduced TC but the results were not significant. The BN25, BN50 and BNBF50 diets also reduced low density lipoprotein (LDL) cholesterol. The BN and BF50 diets reduced liver fat. The BN diets decreased fecal fat excretion while the BF diets increased excretion. This suggests that increased fat excretion might offset the higher total fat and saturated fat of the BF diets to reduce adverse effects on body weight, adipose weight, and cholesterol. The high-fat content of the base (Control) diet may have muted the effects of the diet treatments. Graphical Abstracthttps://doi.org/10.1186/s43014-023-00135-2LegumeMeatCholesterolhamsterMeat alternativeFat |
| spellingShingle | John W. Finley Darryl Holliday Hyunsook Kim Priscila Leal da Silva Alves Dong-Yan Shao Glenn Bartley Wallace Yokoyama Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters Food Production, Processing and Nutrition Legume Meat Cholesterol hamster Meat alternative Fat |
| title | Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| title_full | Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| title_fullStr | Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| title_full_unstemmed | Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| title_short | Substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| title_sort | substitution of cooked kidney beans or ground beef in hypercholesterolemic high fat diets reduces plasma and liver lipids in hamsters |
| topic | Legume Meat Cholesterol hamster Meat alternative Fat |
| url | https://doi.org/10.1186/s43014-023-00135-2 |
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