Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma

Extramammary Paget disease (EMPD) is a rare, cutaneous condition, which can present secondary to underlying carcinoma as an eczematoid rash that often mimics other conditions. Secondary EMPD should, therefore, be considered in the differential diagnosis where there is potential for malignant extens...

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Main Authors: Victoria Dukharan, Adriana L Della Porta, Scott Gregory, Gulsun Erdag
Format: Article
Language:English
Published: European Medical Journal 2022-02-01
Series:European Medical Journal
Online Access:https://www.emjreviews.com/dermatology/article/extramammary-paget-disease-of-peristomal-skin-secondary-to-bladder-urothelial-carcinoma/
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author Victoria Dukharan
Adriana L Della Porta
Scott Gregory
Gulsun Erdag
author_facet Victoria Dukharan
Adriana L Della Porta
Scott Gregory
Gulsun Erdag
author_sort Victoria Dukharan
collection DOAJ
description Extramammary Paget disease (EMPD) is a rare, cutaneous condition, which can present secondary to underlying carcinoma as an eczematoid rash that often mimics other conditions. Secondary EMPD should, therefore, be considered in the differential diagnosis where there is potential for malignant extension, particularly in post-operative tissue. This report describes a case of secondary EMPD of the peristomal skin in a patient with a distant history of cystectomy with ileal conduit for urothelial carcinoma, who developed an extensive eczematoid rash over 5 years after attempting several ineffective treatments. Early dermatologic referral for persistent inflammatory cutaneous disorders and appropriate histopathologic testing may reduce delays in the diagnosis of EMPD.
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spelling doaj.art-6f3f49c8cd374a35ab3e70da7f18faae2024-04-23T15:19:41ZengEuropean Medical JournalEuropean Medical Journal2397-67642022-02-0110.33590/emj/21-00249Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial CarcinomaVictoria Dukharan0Adriana L Della Porta1Scott Gregory2Gulsun Erdag3University of Florida College of Medicine, Gainesville, Florida, USAUniversity of Florida College of Medicine, Gainesville, Florida, USADepartment of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USADepartment of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA; Malcolm Randall Medical Center, Department of Veterans Affairs, Gainesville, Florida, USA Extramammary Paget disease (EMPD) is a rare, cutaneous condition, which can present secondary to underlying carcinoma as an eczematoid rash that often mimics other conditions. Secondary EMPD should, therefore, be considered in the differential diagnosis where there is potential for malignant extension, particularly in post-operative tissue. This report describes a case of secondary EMPD of the peristomal skin in a patient with a distant history of cystectomy with ileal conduit for urothelial carcinoma, who developed an extensive eczematoid rash over 5 years after attempting several ineffective treatments. Early dermatologic referral for persistent inflammatory cutaneous disorders and appropriate histopathologic testing may reduce delays in the diagnosis of EMPD.https://www.emjreviews.com/dermatology/article/extramammary-paget-disease-of-peristomal-skin-secondary-to-bladder-urothelial-carcinoma/
spellingShingle Victoria Dukharan
Adriana L Della Porta
Scott Gregory
Gulsun Erdag
Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
European Medical Journal
title Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
title_full Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
title_fullStr Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
title_full_unstemmed Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
title_short Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma
title_sort extramammary paget disease of peristomal skin secondary to bladder urothelial carcinoma
url https://www.emjreviews.com/dermatology/article/extramammary-paget-disease-of-peristomal-skin-secondary-to-bladder-urothelial-carcinoma/
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AT scottgregory extramammarypagetdiseaseofperistomalskinsecondarytobladderurothelialcarcinoma
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