Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-κB pathway

Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-κB pathway

Abstract Background Obesity is one of the leading causes of insulin resistance. Accumulating reports have highlighted that serum amyloid A-1 (SAA1) is a potential candidate that is capable of attenuating insulin resistance. Hence, we conducted the current study with aims of investigating our propose...

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Bibliographic Details
Main Authors: Yong Wang, Feng Cao, Yang Wang, Gang Yu, Ben-Li Jia
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Medicine
Subjects:
Serum amyloid A-1
NF-κB pathway
Insulin resistance
Palmitate
High-fat diet
Online Access:http://link.springer.com/article/10.1186/s10020-019-0075-4

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http://link.springer.com/article/10.1186/s10020-019-0075-4

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