Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors
Three microwave sensors are used to track the glucose level of different human blood plasma solutions. In this paper, the sensors are evaluated as glucose trackers in a context close to real human blood. Different plasma solutions sets were prepared from a human blood sample at several added glucose...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-08-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/19/17/3779 |
| _version_ | 1818034821095489536 |
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| author | Carlos G. Juan Enrique Bronchalo Benjamin Potelon Cédric Quendo José M. Sabater-Navarro |
| author_facet | Carlos G. Juan Enrique Bronchalo Benjamin Potelon Cédric Quendo José M. Sabater-Navarro |
| author_sort | Carlos G. Juan |
| collection | DOAJ |
| description | Three microwave sensors are used to track the glucose level of different human blood plasma solutions. In this paper, the sensors are evaluated as glucose trackers in a context close to real human blood. Different plasma solutions sets were prepared from a human blood sample at several added glucose concentrations up to 10 wt%, adding also ascorbic acid and lactic acid at different concentrations. The experimental results for the different sensors/solutions combinations are presented in this work. The sensors show good performance and linearity as glucose level retrievers, although the sensitivities change as the rest of components vary. Different sensor behaviors depending upon the concentrations of glucose and other components are identified and characterized. The results obtained in terms of sensitivity are coherent with previous works, highlighting the contribution of glucose to the dielectric losses of the solution. The results are also consistent with the frequency evolution of the electromagnetic signature of glucose found in the literature, and are helpful for selecting frequency bands for sensing purposes and envisioning future approaches to the challenging measurement in real biological contexts. Discussion of the implications of the results and guidelines for further research and development of more accurate sensors is offered. |
| first_indexed | 2024-12-10T06:45:15Z |
| format | Article |
| id | doaj.art-6f4a5964957b4bef9e94e95b72803c03 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-12-10T06:45:15Z |
| publishDate | 2019-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-6f4a5964957b4bef9e94e95b72803c032022-12-22T01:58:40ZengMDPI AGSensors1424-82202019-08-011917377910.3390/s19173779s19173779Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave SensorsCarlos G. Juan0Enrique Bronchalo1Benjamin Potelon2Cédric Quendo3José M. Sabater-Navarro4Department of Systems Engineering and Automation, Miguel Hernández University, 03202 Elche, SpainDepartment of Communications Engineering, Miguel Hernández University, 03202 Elche, SpainLaboratoire des Sciences et Techniques de l’Information de la Communication et de la Connaissance, University of Brest, 29200 Brest, FranceLaboratoire des Sciences et Techniques de l’Information de la Communication et de la Connaissance, University of Brest, 29200 Brest, FranceDepartment of Systems Engineering and Automation, Miguel Hernández University, 03202 Elche, SpainThree microwave sensors are used to track the glucose level of different human blood plasma solutions. In this paper, the sensors are evaluated as glucose trackers in a context close to real human blood. Different plasma solutions sets were prepared from a human blood sample at several added glucose concentrations up to 10 wt%, adding also ascorbic acid and lactic acid at different concentrations. The experimental results for the different sensors/solutions combinations are presented in this work. The sensors show good performance and linearity as glucose level retrievers, although the sensitivities change as the rest of components vary. Different sensor behaviors depending upon the concentrations of glucose and other components are identified and characterized. The results obtained in terms of sensitivity are coherent with previous works, highlighting the contribution of glucose to the dielectric losses of the solution. The results are also consistent with the frequency evolution of the electromagnetic signature of glucose found in the literature, and are helpful for selecting frequency bands for sensing purposes and envisioning future approaches to the challenging measurement in real biological contexts. Discussion of the implications of the results and guidelines for further research and development of more accurate sensors is offered.https://www.mdpi.com/1424-8220/19/17/3779dielectric lossesglucose sensorhuman blood plasmamicrowave resonatormulti-component studypermittivityquality factor |
| spellingShingle | Carlos G. Juan Enrique Bronchalo Benjamin Potelon Cédric Quendo José M. Sabater-Navarro Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors Sensors dielectric losses glucose sensor human blood plasma microwave resonator multi-component study permittivity quality factor |
| title | Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors |
| title_full | Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors |
| title_fullStr | Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors |
| title_full_unstemmed | Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors |
| title_short | Glucose Concentration Measurement in Human Blood Plasma Solutions with Microwave Sensors |
| title_sort | glucose concentration measurement in human blood plasma solutions with microwave sensors |
| topic | dielectric losses glucose sensor human blood plasma microwave resonator multi-component study permittivity quality factor |
| url | https://www.mdpi.com/1424-8220/19/17/3779 |
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