Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles

The increasing penetration of materials and products containing engineered nanoparticles (ENPs) to the market is posing many concerns regarding their environmental impacts. To assess these impacts, there is an urgent need of techniques for determining the health-related properties of ENPs and standa...

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Main Authors: Olga-Ioanna Kalantzi, George Biskos
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Toxics
Subjects:
Online Access:http://www.mdpi.com/2305-6304/2/1/79
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author Olga-Ioanna Kalantzi
George Biskos
author_facet Olga-Ioanna Kalantzi
George Biskos
author_sort Olga-Ioanna Kalantzi
collection DOAJ
description The increasing penetration of materials and products containing engineered nanoparticles (ENPs) to the market is posing many concerns regarding their environmental impacts. To assess these impacts, there is an urgent need of techniques for determining the health-related properties of ENPs and standards for assessing their toxicity. Although a wide number of systems for characterizing nanoparticles in different media (i.e., gases and liquids) is already commercially available, the development of protocols for determining the cytotoxicity of ENPs is still at an infant stage, drawing upon existing knowledge from general toxicology. In this regard, differences in the preparation of ENP-containing solutions for cytotoxicity testing, as well as in the steps involved in the tests can result in significant deviations and inconsistencies between studies. In an attempt to highlight the urgent need for assessing the environmental impacts of nanotechnology, this article provides a brief overview of the existing methods for determining health-related properties of ENPs and their cytotoxicity.
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spelling doaj.art-6f4ab21b9340477987641946215535ff2022-12-22T03:33:40ZengMDPI AGToxics2305-63042014-03-0121799110.3390/toxics2010079toxics2010079Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered NanoparticlesOlga-Ioanna Kalantzi0George Biskos1Department of Environment, University of the Aegean, Mytilene 81100, GreeceDepartment of Environment, University of the Aegean, Mytilene 81100, GreeceThe increasing penetration of materials and products containing engineered nanoparticles (ENPs) to the market is posing many concerns regarding their environmental impacts. To assess these impacts, there is an urgent need of techniques for determining the health-related properties of ENPs and standards for assessing their toxicity. Although a wide number of systems for characterizing nanoparticles in different media (i.e., gases and liquids) is already commercially available, the development of protocols for determining the cytotoxicity of ENPs is still at an infant stage, drawing upon existing knowledge from general toxicology. In this regard, differences in the preparation of ENP-containing solutions for cytotoxicity testing, as well as in the steps involved in the tests can result in significant deviations and inconsistencies between studies. In an attempt to highlight the urgent need for assessing the environmental impacts of nanotechnology, this article provides a brief overview of the existing methods for determining health-related properties of ENPs and their cytotoxicity.http://www.mdpi.com/2305-6304/2/1/79nanotechnologyengineered nanoparticlescytotoxicityhuman exposure
spellingShingle Olga-Ioanna Kalantzi
George Biskos
Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
Toxics
nanotechnology
engineered nanoparticles
cytotoxicity
human exposure
title Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
title_full Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
title_fullStr Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
title_full_unstemmed Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
title_short Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles
title_sort methods for assessing basic particle properties and cytotoxicity of engineered nanoparticles
topic nanotechnology
engineered nanoparticles
cytotoxicity
human exposure
url http://www.mdpi.com/2305-6304/2/1/79
work_keys_str_mv AT olgaioannakalantzi methodsforassessingbasicparticlepropertiesandcytotoxicityofengineerednanoparticles
AT georgebiskos methodsforassessingbasicparticlepropertiesandcytotoxicityofengineerednanoparticles