Promoter Methylation Status and Protein Expression of BRCA2 in Patients with Epithelial Ovarian Cancer

Promoter Methylation Status and Protein Expression of BRCA2 in Patients with Epithelial Ovarian Cancer

Background: Ovarian cancer is the leading cause of death among gynecological cancers. Changes in the methylation of BRCA1 and BRCA2 may be an effective mechanism for breast and ovarian cancer. This study evaluates the protein expression and methylation status of BRCA2 in Iranian patients.Methods: We...

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Bibliographic Details
Main Authors: Ahmad Shabanizadeh, Hajar Dahim, Reza Salahshoor, Zahra Taghipour, Mohammad Mohsen Taghavi, Hamidreza Gafarineveh, Bahram Eslami, Zahra Babazadeh, Farangis Fatehi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2013-01-01
Series:Middle East Journal of Cancer
Subjects:
Ovarian cancer
Tumor suppressor
Methylation
Online Access:http://mejc.sums.ac.ir/index.php/mejc/article/view/138/219

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