Development and validation of a new robust RP-HPLC method for simultaneous quantitation of insulin and pramlintide in non-invasive and smart glucose-responsive microparticles

Development and validation of a new robust RP-HPLC method for simultaneous quantitation of insulin and pramlintide in non-invasive and smart glucose-responsive microparticles

Background and purpose: Since insulin and pramlintide cooperate in glucose hemostasis, co-administration and quantitation of them in pharmaceutical preparations are imperative. A simple, rapid, sensitive, and isocratic RP-HPLC method was developed and validated for simultaneous quantitation of insul...

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Bibliographic Details
Main Authors: Jaber Emami, Maryam Haghighi, Mahboobeh Rostami, Mohsen Minaiyan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
diabetes; insulin; pramlintide; rp-hplc; smart-glucose responsive microparticles.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=6;spage=594;epage=611;aulast=Emami

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